Table S1. Reactions with perturbed keff. A subset of the genome-scale metabolic network was perturbed with respect to keff values, either manually or randomly. (XLSX 17 kb
Containing the Table S3. Summary table of the updates and new features added to the iAA1259 model co...
Metabolic network definition for dynamic model. Description: Definition of reactions, internal and e...
Optimal flux solutions for all simulated data sets, including the corresponding smallest sum of resi...
Figure S1. Scree plot for determining number of archetypes. A notable elbow is observed for five arc...
Table S2. Lagged cross-correlation values. Cross-correlation values for fixed lag time of 1.2 h. (XL...
Comparison of flux variabilities in ColiGS, ColiCore, and ColiPrunedComp for three different growth ...
Reactions, metabolites, the BSR and elementary modes of the reduced Synechocystis model (Synechocyst...
Figure S3. Parameter estimation results. The parallel L-TA optimization procedure successfully estim...
File contains Supplementary figures 1-9 and Supplementary tables 1-8. (PDF 1.8 MB
FASTCORMICS allows fast context-specific metabolic model reconstruction using microarray data. This ...
Figure S1 KEGG analysis of metabolic networks. KEGG analysis identified the most enriched metabolic ...
The initial values given to parameters in the system at the start of each evolutionary simulation wh...
The whole set of data related to the identified motifs and their annotations (before manual curation...
Figure S2. Parameter estimation procedure. We developed a parallel implementation of a metaheuristic...
List of cofactor combinations that were not considered in the reaction equations for the determinati...
Containing the Table S3. Summary table of the updates and new features added to the iAA1259 model co...
Metabolic network definition for dynamic model. Description: Definition of reactions, internal and e...
Optimal flux solutions for all simulated data sets, including the corresponding smallest sum of resi...
Figure S1. Scree plot for determining number of archetypes. A notable elbow is observed for five arc...
Table S2. Lagged cross-correlation values. Cross-correlation values for fixed lag time of 1.2 h. (XL...
Comparison of flux variabilities in ColiGS, ColiCore, and ColiPrunedComp for three different growth ...
Reactions, metabolites, the BSR and elementary modes of the reduced Synechocystis model (Synechocyst...
Figure S3. Parameter estimation results. The parallel L-TA optimization procedure successfully estim...
File contains Supplementary figures 1-9 and Supplementary tables 1-8. (PDF 1.8 MB
FASTCORMICS allows fast context-specific metabolic model reconstruction using microarray data. This ...
Figure S1 KEGG analysis of metabolic networks. KEGG analysis identified the most enriched metabolic ...
The initial values given to parameters in the system at the start of each evolutionary simulation wh...
The whole set of data related to the identified motifs and their annotations (before manual curation...
Figure S2. Parameter estimation procedure. We developed a parallel implementation of a metaheuristic...
List of cofactor combinations that were not considered in the reaction equations for the determinati...
Containing the Table S3. Summary table of the updates and new features added to the iAA1259 model co...
Metabolic network definition for dynamic model. Description: Definition of reactions, internal and e...
Optimal flux solutions for all simulated data sets, including the corresponding smallest sum of resi...