FASTCORMICS allows fast context-specific metabolic model reconstruction using microarray data. This files furthermore contains: Table S1. Essentiality testing of different cancer models, Table S3. Hypergeometric test quantifying the enrichment of neoplasia related genes retrieved from DisGeNet, Table S6. Summary of the monocyte-macrophage models, Table S7. Confidence level of the included and excluded reactions of the monocytes macrophage models, as well as Figure S1. FASTCORMICS workflow, Figure S2. Correlation plot of predicted lactate secretion rates by context-specific cancer cell models and measured lactate secretion rates, Figure S3. Scatterplot of the fraction of active reactions in monocyte derived macrophages versus the fraction of...
Methods and Figures. Figure S1. Phenotypic and molecular characteristics of HCC cell lines. Figure S...
List of model specific metabolites. Related to Fig. 2. Model specific metabolites were determined b...
Table S1. MISSIONÂŽ shRNA pLKO-puro transduction particles. Table S2. Open Reading Frame Clone Expre...
Reconstructed models in SBML format. The zipped file with 3 subfolders (cancer, monocyte and macroph...
List of selected 156 arrays ordered in function the Jaccard similarity index used for Fig. 1 and of ...
Medium composition and biomass formulation. The biomass equations are given with the metabolites abb...
Mouse models used in the study. Related to Fig. 1. This table includes the mouse models and the num...
peer reviewedBackground: The reconstruction of context-specific metabolic models from easily and rel...
Figure S1.. Expression levels of selected differentially expressed macrophage marker genes after hie...
Raw data for CZE-MS/MS and list of significantly different metabolites from epithelial cells to adip...
CRISPR models. Excel table containing statistically significant predictive models found using the CR...
Raw data for GC/LC-MS/MS metabolomics. Related to Figs. 1 and 2. This table contains all the GC/LC-...
PCA loadings for human TAMs. Loadings of the 237 genes used in the PCA of Fig. 3a. (XLSX 22 kb
The correlation of gene expression and immune cell proportion in key lipid metabolism pathways. (...
Flow cytometry analysis of CD14 + cells differentiated for 5 days with or without 50 % conditioned m...
Methods and Figures. Figure S1. Phenotypic and molecular characteristics of HCC cell lines. Figure S...
List of model specific metabolites. Related to Fig. 2. Model specific metabolites were determined b...
Table S1. MISSIONÂŽ shRNA pLKO-puro transduction particles. Table S2. Open Reading Frame Clone Expre...
Reconstructed models in SBML format. The zipped file with 3 subfolders (cancer, monocyte and macroph...
List of selected 156 arrays ordered in function the Jaccard similarity index used for Fig. 1 and of ...
Medium composition and biomass formulation. The biomass equations are given with the metabolites abb...
Mouse models used in the study. Related to Fig. 1. This table includes the mouse models and the num...
peer reviewedBackground: The reconstruction of context-specific metabolic models from easily and rel...
Figure S1.. Expression levels of selected differentially expressed macrophage marker genes after hie...
Raw data for CZE-MS/MS and list of significantly different metabolites from epithelial cells to adip...
CRISPR models. Excel table containing statistically significant predictive models found using the CR...
Raw data for GC/LC-MS/MS metabolomics. Related to Figs. 1 and 2. This table contains all the GC/LC-...
PCA loadings for human TAMs. Loadings of the 237 genes used in the PCA of Fig. 3a. (XLSX 22 kb
The correlation of gene expression and immune cell proportion in key lipid metabolism pathways. (...
Flow cytometry analysis of CD14 + cells differentiated for 5 days with or without 50 % conditioned m...
Methods and Figures. Figure S1. Phenotypic and molecular characteristics of HCC cell lines. Figure S...
List of model specific metabolites. Related to Fig. 2. Model specific metabolites were determined b...
Table S1. MISSIONÂŽ shRNA pLKO-puro transduction particles. Table S2. Open Reading Frame Clone Expre...