(A) Representative IHC stainings of tumor specimens with a high number of CD8+ cells and a low number of CD8+ cells are shown. (B) Representative IHC stainings of tumor specimens with a high number of PD-1+ cells and a low number of PD-1+ cells are shown. Scale bar, 100 μm. (C) Kaplan-Meier DFS and OS curves stratified by the number of CD8+ cells adjacent to the tumor (n = 54) are shown. (D) Kaplan-Meier DFS and OS curves stratified by the number of PD-1+ cells adjacent to the tumor (n = 54) are shown. The log-rank test was performed for the univariate analysis.</p
The TSA Opal multiplex immunohistochemistry (mIHC) protocol (PerkinElmer) has been used to character...
The TSA Opal multiplex immunohistochemistry (mIHC) protocol (PerkinElmer) has been used to character...
<p>A. 2+ score: weak-to-moderate complete membrane staining in more than 10% of tumor cells (objX40)...
Representative IHC stainings of tumor specimens with high expression of PD-L1 on immune cells (A) an...
Microscopic images showing high- and low-infiltration groups with CD8+, CD4+, FOXP3+, and CD68+ cell...
<p>a. The representative slides of immunohistochemical staining of CD8 each treatment group are show...
<p>High and low density of CD3+ (T cells), CD4+ (T cells), CD8+ (T cells) and CD20+ (B cells) shown ...
(A) PD-L1 expression by IHC on both TC and IC for each subgroup. (B) PD-L1 IHC scoring criteria on T...
Tumor cells with weak signal (intensity 1) are in the yellow circle, and tumor cells with strong sig...
<p>Staining was observed in tumor cell compartment (T), stromal compartment (S) and in tumor endothe...
<p><b>A</b>: Percentage of positive cells for each biomarker in “All Cells” (tumor nest and TME comp...
(A). CDH3. There is no staining in the differentiated (*) or the less differentiates areas (#) of th...
<p>A: IHC score = 0. B: IHC score = 1. C: IHC score = 2. D: Results of IHC scoring in cancer tissue ...
<p>Scattered and dense staining pattern for two p53 immunoreactive tumors. (A) Scattered type. Singl...
<p>High and low density of CD68+ (tumor-associated macrophages, TAM) (A) and CD206+ (M2 subtype of T...
The TSA Opal multiplex immunohistochemistry (mIHC) protocol (PerkinElmer) has been used to character...
The TSA Opal multiplex immunohistochemistry (mIHC) protocol (PerkinElmer) has been used to character...
<p>A. 2+ score: weak-to-moderate complete membrane staining in more than 10% of tumor cells (objX40)...
Representative IHC stainings of tumor specimens with high expression of PD-L1 on immune cells (A) an...
Microscopic images showing high- and low-infiltration groups with CD8+, CD4+, FOXP3+, and CD68+ cell...
<p>a. The representative slides of immunohistochemical staining of CD8 each treatment group are show...
<p>High and low density of CD3+ (T cells), CD4+ (T cells), CD8+ (T cells) and CD20+ (B cells) shown ...
(A) PD-L1 expression by IHC on both TC and IC for each subgroup. (B) PD-L1 IHC scoring criteria on T...
Tumor cells with weak signal (intensity 1) are in the yellow circle, and tumor cells with strong sig...
<p>Staining was observed in tumor cell compartment (T), stromal compartment (S) and in tumor endothe...
<p><b>A</b>: Percentage of positive cells for each biomarker in “All Cells” (tumor nest and TME comp...
(A). CDH3. There is no staining in the differentiated (*) or the less differentiates areas (#) of th...
<p>A: IHC score = 0. B: IHC score = 1. C: IHC score = 2. D: Results of IHC scoring in cancer tissue ...
<p>Scattered and dense staining pattern for two p53 immunoreactive tumors. (A) Scattered type. Singl...
<p>High and low density of CD68+ (tumor-associated macrophages, TAM) (A) and CD206+ (M2 subtype of T...
The TSA Opal multiplex immunohistochemistry (mIHC) protocol (PerkinElmer) has been used to character...
The TSA Opal multiplex immunohistochemistry (mIHC) protocol (PerkinElmer) has been used to character...
<p>A. 2+ score: weak-to-moderate complete membrane staining in more than 10% of tumor cells (objX40)...