(A) PD-L1 expression by IHC on both TC and IC for each subgroup. (B) PD-L1 IHC scoring criteria on TC and IC (3) (C) Overall prevalence of overlapping PD-L1 subgroups. (D) Percentages in Venn diagrams represent the prevalence of PD-L1 expression by TC and IC in overlapping subgroups. (E) Overall prevalence of CD8 infiltration in the tumor center.</p
<p>Examples of the evaluation of tumor infiltrating lymphocytes(TILs) in the present study. The mean...
<p>Top panel: Box plot of the proportion of cytokeratin+ cells coexpressing CD44 and CD90. CD44+/CD9...
Objectives: We investigated the PD-L1 expression in colorectal cancer (CRC) and in its microenvironm...
<p><b>A</b>: Pattern I—Constitutive mixed with induced. Diffuse expression of PD-L1 (IHC) on tumor c...
<p><b>A</b>: Percentage of positive cells for each biomarker in “All Cells” (tumor nest and TME comp...
(A) Representative IHC stainings of tumor specimens with a high number of CD8+ cells and a low numbe...
In normal cell physiology, programmed death 1 (PD-1) and its ligand, PD-L1, play an immunoregulatory...
Representative IHC stainings of tumor specimens with high expression of PD-L1 on immune cells (A) an...
<p>A-B)Examples of double staining immunohistochemistry to identify M1 and M2 TAMs in cervical cance...
The TSA Opal multiplex immunohistochemistry (mIHC) protocol (PerkinElmer) has been used to character...
Programmed death ligand-1 (PD-L1) expression as determined by immunohistochemistry (IHC) is potentia...
<p>Correlation between tumor PD-L1 expression and intratumoral CD8+ T lymphocyte count.</p
(A) Relative mRNA expression of CD274 and CD8 infiltration in TC3 tumors based on various levels of ...
<p>Representatives examples of Hematoxylin eosin immunohistochemical PD-L1 staining in cytoplasm, me...
Microscopic images showing high- and low-infiltration groups with CD8+, CD4+, FOXP3+, and CD68+ cell...
<p>Examples of the evaluation of tumor infiltrating lymphocytes(TILs) in the present study. The mean...
<p>Top panel: Box plot of the proportion of cytokeratin+ cells coexpressing CD44 and CD90. CD44+/CD9...
Objectives: We investigated the PD-L1 expression in colorectal cancer (CRC) and in its microenvironm...
<p><b>A</b>: Pattern I—Constitutive mixed with induced. Diffuse expression of PD-L1 (IHC) on tumor c...
<p><b>A</b>: Percentage of positive cells for each biomarker in “All Cells” (tumor nest and TME comp...
(A) Representative IHC stainings of tumor specimens with a high number of CD8+ cells and a low numbe...
In normal cell physiology, programmed death 1 (PD-1) and its ligand, PD-L1, play an immunoregulatory...
Representative IHC stainings of tumor specimens with high expression of PD-L1 on immune cells (A) an...
<p>A-B)Examples of double staining immunohistochemistry to identify M1 and M2 TAMs in cervical cance...
The TSA Opal multiplex immunohistochemistry (mIHC) protocol (PerkinElmer) has been used to character...
Programmed death ligand-1 (PD-L1) expression as determined by immunohistochemistry (IHC) is potentia...
<p>Correlation between tumor PD-L1 expression and intratumoral CD8+ T lymphocyte count.</p
(A) Relative mRNA expression of CD274 and CD8 infiltration in TC3 tumors based on various levels of ...
<p>Representatives examples of Hematoxylin eosin immunohistochemical PD-L1 staining in cytoplasm, me...
Microscopic images showing high- and low-infiltration groups with CD8+, CD4+, FOXP3+, and CD68+ cell...
<p>Examples of the evaluation of tumor infiltrating lymphocytes(TILs) in the present study. The mean...
<p>Top panel: Box plot of the proportion of cytokeratin+ cells coexpressing CD44 and CD90. CD44+/CD9...
Objectives: We investigated the PD-L1 expression in colorectal cancer (CRC) and in its microenvironm...