Activity of IVM at homo- and heteromeric GluClRs.

(A-C) Representative concentration-response experiments at the indicated IVM concentrations in oocytes. IVM-induced currents were normalised to the response elicited by a saturating concentration of glutamate (5 mM) for oocytes injected with cDNA encoding the α subunit (A) or α and β subunits at a ratio of 1:50 (B) or 1:1 (C). D. Group concentration-response data for the indicated GluClRs. Holding potential was −40 mV.