Differential abundance plots of bacterial genera that were statistically significantly different (p< 0.05) between the brands.

The bacterial OTUs that could not be assigned to a genus are represented as “Unclassified” and are assigned to their family level. The grey line and arrows highlight the conversion in log2-fold change from negative to positive values. [A] Comparing Cheyenne Menthol Box (CMB) to Cheyenne Full Flavor (CFF) tobacco samples. A positive log2-fold change value denotes an OTU that is significantly higher in CFF, while a negative log2-fold change indicates an OTU that is significantly higher in CMB. [B] Comparing Swisher sweets cherry (SSC) to Swisher sweets original (SSO) tobacco samples. A positive log2-fold change value denotes an OTU that is significantly higher in SSO, while a negative log2-fold change indicates an OTU that is significantly higher in SSC. [C] Comparing Swisher sweets original (SSO) to Cheyenne Full Flavor (CFF) tobacco samples. A positive log2-fold change value denotes an OTU that is significantly higher in CFF, while a negative log2-fold change indicates an OTU that is significantly higher in SSO. [D] Comparing Cheyenne Menthol Box (CMB) to Cheyenne Full Flavor (CFF) wrapper samples. A positive log2-fold change value denotes an OTU that is significantly higher in CFF, while a negative log2-fold change indicates an OTU that is significantly higher in CMB.