Additional file 4: of FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Additional file 4: of 14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling

Jia Song (495396)
Xiaochao Zhang (6046529)
Zhibin Liao (6173411)
Huifang Liang (781781)
Liang Chu (126831)
Wei Dong (6479)
Xuewu Zhang (2310436)
Qianyun Ge (6173414)
Qiumeng Liu (6173417)
Pan Fan (6173420)
Zhanguo Zhang (3138240)
Bixiang Zhang (745204)

January 2019

Figure S3. (a, b, c, d) Western blotting (left panel; a, c) and qRT-PCR (right panel; b, d) were use...

Additional file 11: of PCBP1 depletion promotes tumorigenesis through attenuation of p27Kip1 mRNA stability and translation

Hongshun Shi (5612186)
Hui Li (32376)
Ronghua Yuan (4638010)
Wen Guan (5612195)
Xiaomei Zhang (147359)
Shaoyang Zhang (5612201)
Wenliang Zhang (50782)
Fang Tong (484200)
Li Li (14993)
Zhihong Song (2305513)
Changwei Wang (1619869)
Shulan Yang (5612213)
Haihe Wang (5612216)

August 2018

Figure S9. Relationship of PCBP1 to p27 mRNA level in tumor samples. (A). Semiquantitative RT-PCR de...

Additional file 1: of BMP4 promotes hepatocellular carcinoma proliferation by autophagy activation through JNK1-mediated Bcl-2 phosphorylation

Ganlu Deng (3464573)
Shan Zeng (3464564)
Yanling Qu (5519885)
Qingqing Luo (5519894)
Cao Guo (3464567)
Ling Yin (416656)
Ying Han (137520)
Yiyi Li (1968925)
Changjing Cai (5519888)
Yaojie Fu (5519891)
Hong Shen (166278)

July 2018

Figure S1. Original blots of Western blot. Original blots of Fig. 1. (2) Original blots of Fig. 2. (...

Additional file 2: of FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Long Zhang (315279)
Jin Chen (130241)
Deng Ning (6404843)
Qiumeng Liu (6173417)
Chao Wang (146527)
Zhaoqi Zhang (332445)
Liang Chu (126831)
Chengpeng Yu (6404855)
Hui-fang Liang (5612702)
Bixiang Zhang (745204)
Xiaoping Chen (42085)

February 2019

Figure S2. FBX022 ubiquitinates p21 and F-box domain mediates the process (a) LM3 cells were treated...

Additional file 3: of FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Long Zhang (315279)
Jin Chen (130241)
Deng Ning (6404843)
Qiumeng Liu (6173417)
Chao Wang (146527)
Zhaoqi Zhang (332445)
Liang Chu (126831)
Chengpeng Yu (6404855)
Hui-fang Liang (5612702)
Bixiang Zhang (745204)
Xiaoping Chen (42085)

February 2019

Figure S3. FBX022 ubiquitinates p21 via the F-box domain HLF (a), HepG2 (b), Hep3B (c) and LM3 cells...

Additional file 1: of FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Long Zhang (315279)
Jin Chen (130241)
Deng Ning (6404843)
Qiumeng Liu (6173417)
Chao Wang (146527)
Zhaoqi Zhang (332445)
Liang Chu (126831)
Chengpeng Yu (6404855)
Hui-fang Liang (5612702)
Bixiang Zhang (745204)
Xiaoping Chen (42085)

February 2019

Figure S1. FBXO22 promotes proliferation and tumorigenesis of HCC cells in vitro and effect of FBXO2...

FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Long Zhang
Jin Chen
Deng Ning
Qiumeng Liu
Chao Wang
Zhaoqi Zhang
Liang Chu
Chengpeng Yu
Hui-fang Liang
Bixiang Zhang
Xiaoping Chen

February 2019

Abstract Background Deregulation of ubiquitin ligases is related to the malignant progression of hum...

Additional file 5: of Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui (5483207)
Robert Martin (4067452)
Hang Jin (524013)
Xingkai Liu (5483204)
Harshul Pandit (5483201)
Hengjun Zhao (5483210)
Lu Cai (158735)
Ping Zhang (86495)
Wei Li (1125347)
Yan Li (23143)

July 2018

Figure S4. Upper: Representative Western blot for β-Klotho proteins detection (AFP, FASN, FGFR4 and ...

Additional file 1: of Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui (5483207)
Robert Martin (4067452)
Hang Jin (524013)
Xingkai Liu (5483204)
Harshul Pandit (5483201)
Hengjun Zhao (5483210)
Lu Cai (158735)
Ping Zhang (86495)
Wei Li (1125347)
Yan Li (23143)

July 2018

Tables S1-S3, list of antibodies, promers and siRNAs. Method for ultrasound image acquisition. Figur...

Additional file 4: of Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui (5483207)
Robert Martin (4067452)
Hang Jin (524013)
Xingkai Liu (5483204)
Harshul Pandit (5483201)
Hengjun Zhao (5483210)
Lu Cai (158735)
Ping Zhang (86495)
Wei Li (1125347)
Yan Li (23143)

July 2018

Figure S3. Representative images of EpCAM and Î˛-Catenin in liver parenchyma in all 4 experimental g...

Additional file 3: of Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui (5483207)
Robert Martin (4067452)
Hang Jin (524013)
Xingkai Liu (5483204)
Harshul Pandit (5483201)
Hengjun Zhao (5483210)
Lu Cai (158735)
Ping Zhang (86495)
Wei Li (1125347)
Yan Li (23143)

July 2018

Figure S2. The body weights, liver weights, serum and tissue triglyceride levels, alpha fetoprotein ...

Additional file 1: of FOXM1 promotes hepatocellular carcinoma progression by regulating KIF4A expression

Guohui Hu (3711253)
Zhengwei Yan (6687233)
Cheng Zhang (70708)
Minzhang Cheng (5845784)
Yehong Yan (6687236)
Yiting Wang (169115)
Libin Deng (522588)
Quqin Lu (522585)
Shiwen Luo (522591)

May 2019

Table S1. HCC datasets downloaded from NCBI GEO. Table S2. The shRNAs used for specific genes knockd...

Additional file 2: of Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui (5483207)
Robert Martin (4067452)
Hang Jin (524013)
Xingkai Liu (5483204)
Harshul Pandit (5483201)
Hengjun Zhao (5483210)
Lu Cai (158735)
Ping Zhang (86495)
Wei Li (1125347)
Yan Li (23143)

July 2018

Figure S1. Representative gross anatomy and ultrasound images from all 4 experimental groups at mont...

Additional file 3: of Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

Sofie Bagger (6067151)
Branden Hopkinson (2284195)
Deo Pandey (6067154)
Mads Bak (181535)
Andreas Brydholm (6067157)
Rene Villadsen (5649055)
Kristian Helin (10963)
Lone RĂ¸nnov-Jessen (3463754)
Ole Petersen (3463742)
Jiyoung Kim (149493)

December 2018

Table S1. Clinical outcome as a function of FBXO11 expression in breast cancer subtypes and Figure S...

Additional file 5: of 14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling

Jia Song (495396)
Xiaochao Zhang (6046529)
Zhibin Liao (6173411)
Huifang Liang (781781)
Liang Chu (126831)
Wei Dong (6479)
Xuewu Zhang (2310436)
Qianyun Ge (6173414)
Qiumeng Liu (6173417)
Pan Fan (6173420)
Zhanguo Zhang (3138240)
Bixiang Zhang (745204)

January 2019

Figure S4. (a, b) qRT-PCR was used to analyze in HCC HLF(a) and Bel7402(b) cells for mRNA levels of ...

Additional file 4: of 14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling

Jia Song (495396)
Xiaochao Zhang (6046529)
Zhibin Liao (6173411)
Huifang Liang (781781)
Liang Chu (126831)
Wei Dong (6479)
Xuewu Zhang (2310436)
Qianyun Ge (6173414)
Qiumeng Liu (6173417)
Pan Fan (6173420)
Zhanguo Zhang (3138240)
Bixiang Zhang (745204)

January 2019

Figure S3. (a, b, c, d) Western blotting (left panel; a, c) and qRT-PCR (right panel; b, d) were use...

Additional file 11: of PCBP1 depletion promotes tumorigenesis through attenuation of p27Kip1 mRNA stability and translation

Hongshun Shi (5612186)
Hui Li (32376)
Ronghua Yuan (4638010)
Wen Guan (5612195)
Xiaomei Zhang (147359)
Shaoyang Zhang (5612201)
Wenliang Zhang (50782)
Fang Tong (484200)
Li Li (14993)
Zhihong Song (2305513)
Changwei Wang (1619869)
Shulan Yang (5612213)
Haihe Wang (5612216)

August 2018

Figure S9. Relationship of PCBP1 to p27 mRNA level in tumor samples. (A). Semiquantitative RT-PCR de...

Additional file 1: of BMP4 promotes hepatocellular carcinoma proliferation by autophagy activation through JNK1-mediated Bcl-2 phosphorylation

Ganlu Deng (3464573)
Shan Zeng (3464564)
Yanling Qu (5519885)
Qingqing Luo (5519894)
Cao Guo (3464567)
Ling Yin (416656)
Ying Han (137520)
Yiyi Li (1968925)
Changjing Cai (5519888)
Yaojie Fu (5519891)
Hong Shen (166278)

July 2018

Figure S1. Original blots of Western blot. Original blots of Fig. 1. (2) Original blots of Fig. 2. (...

Additional file 2: of FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Long Zhang (315279)
Jin Chen (130241)
Deng Ning (6404843)
Qiumeng Liu (6173417)
Chao Wang (146527)
Zhaoqi Zhang (332445)
Liang Chu (126831)
Chengpeng Yu (6404855)
Hui-fang Liang (5612702)
Bixiang Zhang (745204)
Xiaoping Chen (42085)

February 2019

Figure S2. FBX022 ubiquitinates p21 and F-box domain mediates the process (a) LM3 cells were treated...

Additional file 3: of FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Long Zhang (315279)
Jin Chen (130241)
Deng Ning (6404843)
Qiumeng Liu (6173417)
Chao Wang (146527)
Zhaoqi Zhang (332445)
Liang Chu (126831)
Chengpeng Yu (6404855)
Hui-fang Liang (5612702)
Bixiang Zhang (745204)
Xiaoping Chen (42085)

February 2019

Figure S3. FBX022 ubiquitinates p21 via the F-box domain HLF (a), HepG2 (b), Hep3B (c) and LM3 cells...

Additional file 1: of FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Long Zhang (315279)
Jin Chen (130241)
Deng Ning (6404843)
Qiumeng Liu (6173417)
Chao Wang (146527)
Zhaoqi Zhang (332445)
Liang Chu (126831)
Chengpeng Yu (6404855)
Hui-fang Liang (5612702)
Bixiang Zhang (745204)
Xiaoping Chen (42085)

February 2019

Figure S1. FBXO22 promotes proliferation and tumorigenesis of HCC cells in vitro and effect of FBXO2...

FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Long Zhang
Jin Chen
Deng Ning
Qiumeng Liu
Chao Wang
Zhaoqi Zhang
Liang Chu
Chengpeng Yu
Hui-fang Liang
Bixiang Zhang
Xiaoping Chen

February 2019

Abstract Background Deregulation of ubiquitin ligases is related to the malignant progression of hum...

Additional file 5: of Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui (5483207)
Robert Martin (4067452)
Hang Jin (524013)
Xingkai Liu (5483204)
Harshul Pandit (5483201)
Hengjun Zhao (5483210)
Lu Cai (158735)
Ping Zhang (86495)
Wei Li (1125347)
Yan Li (23143)

July 2018

Figure S4. Upper: Representative Western blot for β-Klotho proteins detection (AFP, FASN, FGFR4 and ...

Additional file 1: of Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui (5483207)
Robert Martin (4067452)
Hang Jin (524013)
Xingkai Liu (5483204)
Harshul Pandit (5483201)
Hengjun Zhao (5483210)
Lu Cai (158735)
Ping Zhang (86495)
Wei Li (1125347)
Yan Li (23143)

July 2018

Tables S1-S3, list of antibodies, promers and siRNAs. Method for ultrasound image acquisition. Figur...

Additional file 4: of Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui (5483207)
Robert Martin (4067452)
Hang Jin (524013)
Xingkai Liu (5483204)
Harshul Pandit (5483201)
Hengjun Zhao (5483210)
Lu Cai (158735)
Ping Zhang (86495)
Wei Li (1125347)
Yan Li (23143)

July 2018

Figure S3. Representative images of EpCAM and Î˛-Catenin in liver parenchyma in all 4 experimental g...

Additional file 3: of Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui (5483207)
Robert Martin (4067452)
Hang Jin (524013)
Xingkai Liu (5483204)
Harshul Pandit (5483201)
Hengjun Zhao (5483210)
Lu Cai (158735)
Ping Zhang (86495)
Wei Li (1125347)
Yan Li (23143)

July 2018

Figure S2. The body weights, liver weights, serum and tissue triglyceride levels, alpha fetoprotein ...

Additional file 1: of FOXM1 promotes hepatocellular carcinoma progression by regulating KIF4A expression

Guohui Hu (3711253)
Zhengwei Yan (6687233)
Cheng Zhang (70708)
Minzhang Cheng (5845784)
Yehong Yan (6687236)
Yiting Wang (169115)
Libin Deng (522588)
Quqin Lu (522585)
Shiwen Luo (522591)

May 2019

Table S1. HCC datasets downloaded from NCBI GEO. Table S2. The shRNAs used for specific genes knockd...

Additional file 2: of Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui (5483207)
Robert Martin (4067452)
Hang Jin (524013)
Xingkai Liu (5483204)
Harshul Pandit (5483201)
Hengjun Zhao (5483210)
Lu Cai (158735)
Ping Zhang (86495)
Wei Li (1125347)
Yan Li (23143)

July 2018

Figure S1. Representative gross anatomy and ultrasound images from all 4 experimental groups at mont...

Additional file 3: of Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

Sofie Bagger (6067151)
Branden Hopkinson (2284195)
Deo Pandey (6067154)
Mads Bak (181535)
Andreas Brydholm (6067157)
Rene Villadsen (5649055)
Kristian Helin (10963)
Lone RĂ¸nnov-Jessen (3463754)
Ole Petersen (3463742)
Jiyoung Kim (149493)

December 2018

Table S1. Clinical outcome as a function of FBXO11 expression in breast cancer subtypes and Figure S...

Additional file 5: of 14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling

Jia Song (495396)
Xiaochao Zhang (6046529)
Zhibin Liao (6173411)
Huifang Liang (781781)
Liang Chu (126831)
Wei Dong (6479)
Xuewu Zhang (2310436)
Qianyun Ge (6173414)
Qiumeng Liu (6173417)
Pan Fan (6173420)
Zhanguo Zhang (3138240)
Bixiang Zhang (745204)

January 2019

Figure S4. (a, b) qRT-PCR was used to analyze in HCC HLF(a) and Bel7402(b) cells for mRNA levels of ...

Additional file 4: of 14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling

Jia Song (495396)
Xiaochao Zhang (6046529)
Zhibin Liao (6173411)
Huifang Liang (781781)
Liang Chu (126831)
Wei Dong (6479)
Xuewu Zhang (2310436)
Qianyun Ge (6173414)
Qiumeng Liu (6173417)
Pan Fan (6173420)
Zhanguo Zhang (3138240)
Bixiang Zhang (745204)

January 2019

Figure S3. (a, b, c, d) Western blotting (left panel; a, c) and qRT-PCR (right panel; b, d) were use...

Additional file 11: of PCBP1 depletion promotes tumorigenesis through attenuation of p27Kip1 mRNA stability and translation

Hongshun Shi (5612186)
Hui Li (32376)
Ronghua Yuan (4638010)
Wen Guan (5612195)
Xiaomei Zhang (147359)
Shaoyang Zhang (5612201)
Wenliang Zhang (50782)
Fang Tong (484200)
Li Li (14993)
Zhihong Song (2305513)
Changwei Wang (1619869)
Shulan Yang (5612213)
Haihe Wang (5612216)

August 2018

Figure S9. Relationship of PCBP1 to p27 mRNA level in tumor samples. (A). Semiquantitative RT-PCR de...

Additional file 1: of BMP4 promotes hepatocellular carcinoma proliferation by autophagy activation through JNK1-mediated Bcl-2 phosphorylation

Ganlu Deng (3464573)
Shan Zeng (3464564)
Yanling Qu (5519885)
Qingqing Luo (5519894)
Cao Guo (3464567)
Ling Yin (416656)
Ying Han (137520)
Yiyi Li (1968925)
Changjing Cai (5519888)
Yaojie Fu (5519891)
Hong Shen (166278)

July 2018

Figure S1. Original blots of Western blot. Original blots of Fig. 1. (2) Original blots of Fig. 2. (...

Additional file 4: of FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Abstract

Extracted data

Additional file 4: of FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Abstract

Extracted data

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