Uptake of 2-DG by HEK293 cells overexpressing PfHT at increasing concentrations of the indicated compounds. IC50s were calculated using nonlinear regression analysis IC50 determinations using GraphPad Prism 6.0. Uptake data are expressed as means ± SEMs (n = 3). Chemical structures of the compounds tested are shown for comparison.</p
Quantitative assessment of myocardial glucose uptake by the glucose tracer analog 2-deoxy-2-[18F]flu...
<p>(A) TIRF microscopy based quantitation of GLUT4 translocation in 3T3-L1 GLUT4-GFP adipocytes. Cel...
Full lines represent the FBA results with the iAF1260 model. Dashed lines illustrate the model of [2...
2-DG uptake in response to increasing WU-1 (A) or WU-2 (B) concentrations in HEK293 cells expressing...
A) Uptake of 2-DG by HEK293 cells overexpressing either PfHT or class III GLUT transporter, hGLUT8. ...
<p>Glucose uptake (A and B) and glycogen storage (C) of HepG2 cells incubated in DMEM with 5.5 mM gl...
<p>Substrate saturation curves (A, B, C) were performed for PfHT in the presence of various concentr...
A) Inhibition of 2-DG uptake by WU-1 in HEK293 cells overexpressing PfHT and FTPfHT. B) Inhibition o...
<p>Glucose uptake was measured in control (A) and CFS (B) cell cultures. Cells from 5 control and 9 ...
<p>(A), (B) The 2DG uptake level in SC cells or KD cells with or without insulin treatment was evalu...
<p>Compounds 1 (A), 7 (B), and 13 (C) were applied over a range from 10<sup>-9</sup>–10<sup>-5</sup>...
<p>Data are presented as the mean ± SD of glucose uptake divided by the optical density determined i...
Glucose transport activity in mammalian cells has been monitored by radiolabeled tracers such as [14...
Cellular glucose uptake was determined in NV and E4 cells treated with no insulin (Control), or trea...
A fluorescence-based enzymatic microplate intracellular glucose assay was designed and fully validat...
Quantitative assessment of myocardial glucose uptake by the glucose tracer analog 2-deoxy-2-[18F]flu...
<p>(A) TIRF microscopy based quantitation of GLUT4 translocation in 3T3-L1 GLUT4-GFP adipocytes. Cel...
Full lines represent the FBA results with the iAF1260 model. Dashed lines illustrate the model of [2...
2-DG uptake in response to increasing WU-1 (A) or WU-2 (B) concentrations in HEK293 cells expressing...
A) Uptake of 2-DG by HEK293 cells overexpressing either PfHT or class III GLUT transporter, hGLUT8. ...
<p>Glucose uptake (A and B) and glycogen storage (C) of HepG2 cells incubated in DMEM with 5.5 mM gl...
<p>Substrate saturation curves (A, B, C) were performed for PfHT in the presence of various concentr...
A) Inhibition of 2-DG uptake by WU-1 in HEK293 cells overexpressing PfHT and FTPfHT. B) Inhibition o...
<p>Glucose uptake was measured in control (A) and CFS (B) cell cultures. Cells from 5 control and 9 ...
<p>(A), (B) The 2DG uptake level in SC cells or KD cells with or without insulin treatment was evalu...
<p>Compounds 1 (A), 7 (B), and 13 (C) were applied over a range from 10<sup>-9</sup>–10<sup>-5</sup>...
<p>Data are presented as the mean ± SD of glucose uptake divided by the optical density determined i...
Glucose transport activity in mammalian cells has been monitored by radiolabeled tracers such as [14...
Cellular glucose uptake was determined in NV and E4 cells treated with no insulin (Control), or trea...
A fluorescence-based enzymatic microplate intracellular glucose assay was designed and fully validat...
Quantitative assessment of myocardial glucose uptake by the glucose tracer analog 2-deoxy-2-[18F]flu...
<p>(A) TIRF microscopy based quantitation of GLUT4 translocation in 3T3-L1 GLUT4-GFP adipocytes. Cel...
Full lines represent the FBA results with the iAF1260 model. Dashed lines illustrate the model of [2...