A. Consumption of inactivated dried yeast interfering RNA syt.427 larvicide tablets induced larval mortality in the L4 larval or pupal stages (days 4–8; compare to larvae fed with control yeast interfering RNA that survived and pupariated). B. Dose-response curves depicting the mass of syt.427 vs. the percentage of A. aegypti larval mortality are shown. LD50 values for syt.427 with upper and lower confidence limits (CL) are indicated. Regression analysis demonstrated that the dose-response data were linearly correlated (R2 = 0.9365). Additional details regarding calculation of lethal doses are provided in the methods section.</p
Quantitative laboratory bioassay methods are required to evaluate the toxicity of novel insecticidal...
<p>5 µM C14 porphyrin solutions were used. PFP (70 mg), either pre-incubated with C14 or untreated, ...
Larval mortality correlates with the extent of suppression, as measured seven days post-exposure. La...
siRNA larvicide #427 was identified in soaking screens for mosquito larval lethal genes. Although co...
Consumption of syt.427 inactivated yeast interfering RNA larvicide tablets induces high levels of mo...
The high levels of Aae syt expression detected throughout the A. aegypti L4 brain (control-treated l...
Additional file 2. A lack of Sac1.1 and otk.16 yeast interfering larvicide activity in A. aegypti la...
<p>The y-axis is the relative growth rate (RGR measured as Δmg/(mg<sub>avg</sub>d) and vertical bars...
<p>The y-axis is the relative growth rate (RGR measured as Δmg/(mg<sub>avg</sub>d) and vertical bars...
Stage L4 larval brains were labeled with mAbnc82 (white in A1, B1; red in A2, B2), which labels syna...
<p>Third instar larvae were intrahemocoelically injected with target and control gene siRNA duplexes...
New mosquito control strategies are vitally needed to address established and emerging arthropod-bor...
<p>The y-axis is the relative growth rate (RGR measured as Δmg/(mg<sub>avg</sub>d) and vertical bars...
New mosquito control strategies are vitally needed to address established and emerging arthropod-bor...
Consumption of syt.427 yeast by D. melanogaster larvae (A) did not impact survival through adult eme...
Quantitative laboratory bioassay methods are required to evaluate the toxicity of novel insecticidal...
<p>5 µM C14 porphyrin solutions were used. PFP (70 mg), either pre-incubated with C14 or untreated, ...
Larval mortality correlates with the extent of suppression, as measured seven days post-exposure. La...
siRNA larvicide #427 was identified in soaking screens for mosquito larval lethal genes. Although co...
Consumption of syt.427 inactivated yeast interfering RNA larvicide tablets induces high levels of mo...
The high levels of Aae syt expression detected throughout the A. aegypti L4 brain (control-treated l...
Additional file 2. A lack of Sac1.1 and otk.16 yeast interfering larvicide activity in A. aegypti la...
<p>The y-axis is the relative growth rate (RGR measured as Δmg/(mg<sub>avg</sub>d) and vertical bars...
<p>The y-axis is the relative growth rate (RGR measured as Δmg/(mg<sub>avg</sub>d) and vertical bars...
Stage L4 larval brains were labeled with mAbnc82 (white in A1, B1; red in A2, B2), which labels syna...
<p>Third instar larvae were intrahemocoelically injected with target and control gene siRNA duplexes...
New mosquito control strategies are vitally needed to address established and emerging arthropod-bor...
<p>The y-axis is the relative growth rate (RGR measured as Δmg/(mg<sub>avg</sub>d) and vertical bars...
New mosquito control strategies are vitally needed to address established and emerging arthropod-bor...
Consumption of syt.427 yeast by D. melanogaster larvae (A) did not impact survival through adult eme...
Quantitative laboratory bioassay methods are required to evaluate the toxicity of novel insecticidal...
<p>5 µM C14 porphyrin solutions were used. PFP (70 mg), either pre-incubated with C14 or untreated, ...
Larval mortality correlates with the extent of suppression, as measured seven days post-exposure. La...