The attempts towards the synthesis of the fragments for total synthesis of Dichocetide C has been reported by two retrosynthetic approaches. First retrosynthetic approach involves reduction of aldehyde to alcohol, bromination of alcohol by appel reaction, hydrogenation of alkene bond and organomagnesium, organozinc and organolithium reactions. Second retrosynthesis approach involves one carbon homologation reaction of aldehydes by Wittig reaction followed by hydrolysis, reduction of aldehyde to alcohol, bromination of alcohol and Grignard reaction. Unfortunately the schemes were failed, the synthesis of the retrons is reported
The dragmacidins are an emerging class of bis(indole) natural products isolated from deep-water mari...
This thesis describes the Smith group\u27s synthetic efforts toward the tedanolides, marine natural ...
The first part of this dissertation deals with employing the use of multi-component coupling reactio...
Dictyoxetane, a structurally novel diterpene, is related to the dollabellane class of natural produc...
The application of the [2,3] Wittig rearrangement to the total synthesis of (+)-discodermolide is th...
This thesis explores the development of the tandem oxy-Cope/ene rearrangement and its application to...
The Cope rearrangement of gem-dimethyl-substituted divinylcyclopropanes has been used to construct f...
The development of efficient strategies for the synthesis of complex organic molecular architectures...
This thesis describes chemoenzymatic formal total syntheses of tetrodotoxin and a concise synthetic ...
The marine sponge-derived polyketide discodermolide is a potent antimitotic agent that represents a ...
AbstractA convergent and flexible synthetic route for the synthesis of C3–C12 fragment of iriomoteol...
One of the many goals of natural product total synthesis, is to leverage modern chemicalmethods to d...
The brown alga, Dictyota dichotoma, collected from the Indian Ocean has proven to be a prolific sour...
International audienceThis account describes an efficient and modulable total synthesis of (+)-disco...
A highly convergent and stereocontrolled total synthesis of ($-$)-discodermolide (1), antipode of po...
The dragmacidins are an emerging class of bis(indole) natural products isolated from deep-water mari...
This thesis describes the Smith group\u27s synthetic efforts toward the tedanolides, marine natural ...
The first part of this dissertation deals with employing the use of multi-component coupling reactio...
Dictyoxetane, a structurally novel diterpene, is related to the dollabellane class of natural produc...
The application of the [2,3] Wittig rearrangement to the total synthesis of (+)-discodermolide is th...
This thesis explores the development of the tandem oxy-Cope/ene rearrangement and its application to...
The Cope rearrangement of gem-dimethyl-substituted divinylcyclopropanes has been used to construct f...
The development of efficient strategies for the synthesis of complex organic molecular architectures...
This thesis describes chemoenzymatic formal total syntheses of tetrodotoxin and a concise synthetic ...
The marine sponge-derived polyketide discodermolide is a potent antimitotic agent that represents a ...
AbstractA convergent and flexible synthetic route for the synthesis of C3–C12 fragment of iriomoteol...
One of the many goals of natural product total synthesis, is to leverage modern chemicalmethods to d...
The brown alga, Dictyota dichotoma, collected from the Indian Ocean has proven to be a prolific sour...
International audienceThis account describes an efficient and modulable total synthesis of (+)-disco...
A highly convergent and stereocontrolled total synthesis of ($-$)-discodermolide (1), antipode of po...
The dragmacidins are an emerging class of bis(indole) natural products isolated from deep-water mari...
This thesis describes the Smith group\u27s synthetic efforts toward the tedanolides, marine natural ...
The first part of this dissertation deals with employing the use of multi-component coupling reactio...