Liječenje PTSP-a

Post-traumatic stress disorder (PTSD) affects individuals that have experienced or witnessed a traumatic event and it affects approximately 7-8 % of the general population. Even more alarming is the PTSD prevalence in military personal throughout the world, with the PTSD prevalence in US combat veterans ranging from 6 to 31%. Severe or untreated PTSD can lead to long- term complications and consequences, including comorbid substance abuse, increased rates of depression and suicide, therefore treatment and potential prevention is key. An exploration of numerous clinical trials concerning the treatment of PTSD is necessary to conclude what the gold standard treatment should be. Considering the fatal consequences that may occur if treatment is not provided, there is great importance in reviewing multiple clinical trials and concluding what the current treatment algorithm should be. PTSD and other psychiatric disorders are not just treated via traditional pharmaceutical ways, but can also involve non-pharmacological, including but not limited to yoga and other forms of exercise. This review aims to explore the current medical treatment and non-medical treatment of PTSD and the effectiveness and safety of the drugs involved.Posttraumatski stresni poremećaj (PTSP) se javlja u osoba koje su proživjele ili bile svjedokom traumatskog događaja, a zahvaća otprilike 7-8% osoba u općoj populaciji. Međutim, posebice zabrinjava činjenica da je prisustvo PTSP-a utvrđeno u čak 6 do 31% američkih ratnih veterana. Težak ili neliječeni PTSP može imati dugotrajne posljedice i komplikacije, poput zlouporabe sredstava ovisnosti, povećane stope obolijevanja od depresivnog poremećaja; stoga je liječenje PTSP-a od presudne važnosti. Neophodne su brojne kliničke studije u oboljelih od PTSP-a, kako bi se utvrdilo koji je zlatni standard liječenja ovog poremećaja. S obzirom na moguće teške posljedice u neliječenih osoba, bitan je sustavni pregled kliničkih studija da bi se sastavio algoritam liječenja. Cilj ovog preglednog rada je prikazati farmakološko i nefarmakološko liječenje PTSP-a, kao i učinkovitost i sigurnost lijekova kojima za sada raspolažemo