In questa review viene stressata l'importanza dell'uso delle MSCs per la rigenerazione ossea e valutati gli effetti delle deacetilasi istoniche e del pathway di Wnt per l'ossificazione.In this concise review, we highlight the importance of the use of MSCs in bone diseases, focusing on the role of histone deacetylases and Wnt pathways involved in osteogenesis. A better understanding of MSC biology and osteogenesis is needed in order to develop new and targeted therapeutic strategies for the treatment of bone diseases/disorder
Bone is a dynamic tissue that must respond to developmental, repair, and remodeling cues in a rapid ...
Osteoporosis is a complex disease characterized by low bone mass, microarchitectural deterioration, ...
Osteocytes are the most abundant (~95%) cells in bone with the longest half-life (~25 years) in huma...
Bone defects are one of the most serious pathologies that need tissue regeneration therapies. Studie...
The human skeleton undergoes continuous bone remodeling, a process relying on orchestrated balance b...
The Wnt pathway is involved in several processes essential for bone development and homeostasis. For...
The skeleton as an organ is widely distributed throughout the entire vertebrate body. Wnt signaling ...
Human mesenchymal stem cells (hMSCs) from bone marrow are a source of osteoblast progenitors in vivo...
Abstract. Wnt signaling is involved not only in embryonic development but also in maintenance of hom...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
Osteoblast differentiation is predominantly regulated by the WNT/β-catenin signaling (canonical WNT ...
The WNT-signaling pathway is involved in cellular and tissue functions that control such diverse pro...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
Wnt signalling has an essential role in regulating bone formation and remodelling during embryonic d...
Bone is a dynamic tissue that must respond to developmental, repair, and remodeling cues in a rapid ...
Osteoporosis is a complex disease characterized by low bone mass, microarchitectural deterioration, ...
Osteocytes are the most abundant (~95%) cells in bone with the longest half-life (~25 years) in huma...
Bone defects are one of the most serious pathologies that need tissue regeneration therapies. Studie...
The human skeleton undergoes continuous bone remodeling, a process relying on orchestrated balance b...
The Wnt pathway is involved in several processes essential for bone development and homeostasis. For...
The skeleton as an organ is widely distributed throughout the entire vertebrate body. Wnt signaling ...
Human mesenchymal stem cells (hMSCs) from bone marrow are a source of osteoblast progenitors in vivo...
Abstract. Wnt signaling is involved not only in embryonic development but also in maintenance of hom...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
Osteoblast differentiation is predominantly regulated by the WNT/β-catenin signaling (canonical WNT ...
The WNT-signaling pathway is involved in cellular and tissue functions that control such diverse pro...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
Wnt signalling has an essential role in regulating bone formation and remodelling during embryonic d...
Bone is a dynamic tissue that must respond to developmental, repair, and remodeling cues in a rapid ...
Osteoporosis is a complex disease characterized by low bone mass, microarchitectural deterioration, ...
Osteocytes are the most abundant (~95%) cells in bone with the longest half-life (~25 years) in huma...