Bone defects are one of the most serious pathologies that need tissue regeneration therapies. Studies on mesenchymal stem cells are changing the way we treat bone diseases. MSCs have been used for the treatment of osteogenesis imperfecta, hypophosphatasia, osteonecrosis of the femoral head, osteoporosis, rheumatoid arthritis and osteoarthritis. In this context, it is becoming ever more clear that the future of therapies will be based on the use of stem cells. In this concise review, we highlight the importance of the use of MSCs in bone diseases, focusing on the role of histone deacetylases and Wnt pathways involved in osteogenesis. A better understanding of MSC biology and osteogenesis is needed in order to develop new and targeted therape...
Background/Aims: We have demonstrated that bone morphogenetic protein 9 (BMP9) is one of the most po...
During bone modeling, remodeling, and bone fracture repair, mesenchymal stem cells (MSCs) differenti...
Osteocytes are the most abundant (~95%) cells in bone with the longest half-life (~25 years) in huma...
In questa review viene stressata l'importanza dell'uso delle MSCs per la rigenerazione ossea e valut...
The human skeleton undergoes continuous bone remodeling, a process relying on orchestrated balance b...
This review focuses on the osteogenic differentiation of mesenchymal stem cells (MSC), bone formatio...
This review focuses on the osteogenic differentiation of mesenchymal stem cells (MSC), bone formatio...
Human mesenchymal stem cells (hMSCs) from bone marrow are a source of osteoblast progenitors in vivo...
Bone marrow transplantation (BMT) has changed the course of treatment for an array of diseases, incl...
Bone is a dynamic tissue that must respond to developmental, repair, and remodeling cues in a rapid ...
Bone marrow transplantation (BMT) has changed the course of treatment for an array of diseases, incl...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
The interacting molecular pathways which control bone remodeling in physiological conditions during ...
Background/Aims: We have demonstrated that bone morphogenetic protein 9 (BMP9) is one of the most po...
During bone modeling, remodeling, and bone fracture repair, mesenchymal stem cells (MSCs) differenti...
Osteocytes are the most abundant (~95%) cells in bone with the longest half-life (~25 years) in huma...
In questa review viene stressata l'importanza dell'uso delle MSCs per la rigenerazione ossea e valut...
The human skeleton undergoes continuous bone remodeling, a process relying on orchestrated balance b...
This review focuses on the osteogenic differentiation of mesenchymal stem cells (MSC), bone formatio...
This review focuses on the osteogenic differentiation of mesenchymal stem cells (MSC), bone formatio...
Human mesenchymal stem cells (hMSCs) from bone marrow are a source of osteoblast progenitors in vivo...
Bone marrow transplantation (BMT) has changed the course of treatment for an array of diseases, incl...
Bone is a dynamic tissue that must respond to developmental, repair, and remodeling cues in a rapid ...
Bone marrow transplantation (BMT) has changed the course of treatment for an array of diseases, incl...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions during ...
The interacting molecular pathways which control bone remodeling in physiological conditions during ...
Background/Aims: We have demonstrated that bone morphogenetic protein 9 (BMP9) is one of the most po...
During bone modeling, remodeling, and bone fracture repair, mesenchymal stem cells (MSCs) differenti...
Osteocytes are the most abundant (~95%) cells in bone with the longest half-life (~25 years) in huma...