Damage resulting from flood events is increasing world-wide, requiring the implementation of mitigation and adaption measures. To facilitate their implementation, it is essential to correctly model flood hazard at the large scale, yet fine spatial resolution. To reduce the computational load of models, flexible meshes are an efficient means compared to uniform regular grids. Yet, thus far they have been applied only for bespoke small-scale studies requiring a high level of a priori grid preparation. To better understand possible advantages as well as shortcomings of their application for large-scale riverine inundation simulations, three different flexible meshes were derived from Height Above Nearest Drainage (HAND) data and compared with ...