This thesis describes the development of methods using divalent samarium reagents in organic synthesis. The main focus is placed on functional group reductions, but reductive formation of carbon-carbon bonds has also been investigated. The reduction of aliphatic nitro compounds was successfully performed using SmI2, amine and water giving the resulting amine in high yield (90%). The reaction was found to tolerate a wide range of other functional groups. The reductive cleavage of benzyl heteroatom bonds using SmI2, amine and water was mechanistically studied and it was found that the reaction order was unity in all components. Furthermore, water displayed a complex relationship and was found to inhibit the reaction at high concentration. T...
Reduction of N,N′-di(2,6-diisopropylphenyl)carbodiimide (DippNCNDipp) by [SmL2(thf)2] (1) (L = N,N′-...
Samarium(II) iodide–water–amine reagents have emerged as some of the most powerful reagents (<i>E</...
The aim of this project was the synthesis a range of carbocycles from carbohydrates using SmI2 as th...
In little more than twenty-five years, samarium(II) iodide (SmI 2) has become a benchmark reducing a...
Samarium diiodide (SmI2) is one of the most widely used single-electron reductants available to orga...
Recent work from our laboratories has shown SmI2–H2O to be a versatile, readily-accessible and non-t...
Nitrogen heterocycles represent vital structural motifs in biologically-active natural products and ...
Three efficient methods for synthesis of five membered carbocycles, a highly understudied product mo...
Despite the broad utility and application of SmI2in synthesis, the reagent is used in stoichiometric...
Samarium(II) iodide–water and samarium(II) iodide–water–amine complexes have been recognized as va...
A new linker design for solid phase synthesis has been developed that is cleaved under mild, neutral...
This study presents three efficient methods for five‐membered ring carbocycle synthesis using samari...
Studies based on radical-induced ring openings of halolactones, spirocyclobutanones, and Rh$\sb2$(OA...
Samarium(II) iodide (SmI<sub>2</sub>) is one of the most important reducing agents in organic synth...
This thesis describes the synthesis, characterisation and reactivity of a range of samarium(II) and ...
Reduction of N,N′-di(2,6-diisopropylphenyl)carbodiimide (DippNCNDipp) by [SmL2(thf)2] (1) (L = N,N′-...
Samarium(II) iodide–water–amine reagents have emerged as some of the most powerful reagents (<i>E</...
The aim of this project was the synthesis a range of carbocycles from carbohydrates using SmI2 as th...
In little more than twenty-five years, samarium(II) iodide (SmI 2) has become a benchmark reducing a...
Samarium diiodide (SmI2) is one of the most widely used single-electron reductants available to orga...
Recent work from our laboratories has shown SmI2–H2O to be a versatile, readily-accessible and non-t...
Nitrogen heterocycles represent vital structural motifs in biologically-active natural products and ...
Three efficient methods for synthesis of five membered carbocycles, a highly understudied product mo...
Despite the broad utility and application of SmI2in synthesis, the reagent is used in stoichiometric...
Samarium(II) iodide–water and samarium(II) iodide–water–amine complexes have been recognized as va...
A new linker design for solid phase synthesis has been developed that is cleaved under mild, neutral...
This study presents three efficient methods for five‐membered ring carbocycle synthesis using samari...
Studies based on radical-induced ring openings of halolactones, spirocyclobutanones, and Rh$\sb2$(OA...
Samarium(II) iodide (SmI<sub>2</sub>) is one of the most important reducing agents in organic synth...
This thesis describes the synthesis, characterisation and reactivity of a range of samarium(II) and ...
Reduction of N,N′-di(2,6-diisopropylphenyl)carbodiimide (DippNCNDipp) by [SmL2(thf)2] (1) (L = N,N′-...
Samarium(II) iodide–water–amine reagents have emerged as some of the most powerful reagents (<i>E</...
The aim of this project was the synthesis a range of carbocycles from carbohydrates using SmI2 as th...