Haplotypes and Polymorphisms Flanking MAp19 Exon 5

. polymorphisms with multiplex sequence-specific PCR in 219 Brazilian leprosy patients (131 lepromatous, 29 borderline, 21 tuberculoid, 14 undetermined, 24 unspecified), 405 healthy Brazilians and 291 Danish blood donors with previously determined MASP-2 and MAp19 levels. We also evaluated MASP-2 levels in further 46 leprosy patients and 69 Brazilian controls., were more frequent in the lepromatous than in other patients (P = 0.008, OR = 8.8). genotypes and MASP-2 levels might thus be of prognostic value for leprosy progression