Additional file 9: of Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation
- Xirui Liu (5225102)
- Yingjian Liang (300784)
- Ruipeng Song (300788)
- Guangchao Yang (5225111)
- Jihua Han (813010)
- Yaliang Lan (5225114)
- Shangha Pan (201039)
- Mingxi Zhu (5225108)
- Yao Liu (173014)
- Yan Wang (15435)
- Fanzheng Meng (635696)
- Yifeng Cui (5225105)
- Jiabei Wang (345448)
- Bo Zhang (6559)
- Xuan Song (345451)
- Zhaoyang Lu (345450)
- Tongsen Zheng (345447)
- Lianxin Liu (300790)
Publication date
May 2018
DOIAbstract
Figure S7. NEAT1 is a TP53 target gene in HCC. A. The expression of NEAT1 was higher in TP53 wild-type tissues (n = 26) than in the TP-53 mutant liver tissues (n = 14). B. Treatment with Nutlin-3a resulted in higher NEAT1 levels in TP53 wild-type Hep-G2 and SK-hep-1 cells but not in TP53 mutant Huh7 and HCCLM3 cells. C. Western blot analysis determined TP53 was upregulated following NEAT1 knockdown in SK-Hep-1 and Hep-G2 cells. D. Western blot analysis determined p21 and Bax was upregulated following NEAT1 knockdown in SK-Hep-1 and Hep-G2 cells. Data are expressed as mean ± SD of three independent experiments. Statistical significance was concluded at *P < 0.05, **P < 0.01, NS represents no statistical significance. (TIF 530 kb
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