Simulations of IDs, each consisting of separate short bursts.

<p>(<b>A</b>) The nominal depolarization (top plot), the intracellular sodium (red line) and extracellular potassium (blue) concentrations (bottom, left axis), and the ionic flux through the Na-K-pump (orange line, bottom plot, right axis) during six IDs. (<b>B</b>) The population firing rate (black), the nominal depolarization (red), and the synaptic resource (violet) during a single ID consisting of some SBs. (<b>C</b>) Zoomed traces from A, bottom during a single ID. Simulations were done with Eqs <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006186#pcbi.1006186.e001" target="_blank">1</a>–<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006186#pcbi.1006186.e008" target="_blank">8</a> with the basic parameter set. Note the decrease of [<i>K</i>]_<i>o</i> at the high level of peaks of <i>I</i>_<i>pump</i> and following the termination of the ID.