<p>In this case there are no hidden transitions, and hence no stochastic shielding effect. <b>Left column:</b> 3-state diagram with accelerated/decelerated edges labeled as 1 or <i>α</i> where <i>α</i> ∈ [10<sup>−4</sup>, 10<sup>4</sup>]. <b>Middle column:</b> logarithm of ratio of the two non-zero eigenvalues (λ<sub>2</sub>/λ<sub>3</sub>) versus <i>α</i>. This shows the timescale separation (present when λ<sub>2</sub>/λ<sub>3</sub> ≪ 1). <b>Right column:</b> relative edge importance <i>R</i><sub><i>k</i></sub> versus <i>α</i>.</p
<p>Due to rounding the presented transition probabilities may not sum perfectly to 1.00.</p
Scenario 3, states B (left) and C (right) of the simple reaction model: Normalised state classificat...
<p>For a low concentration ([ACh] = 0.5 <i>μ</i>M shown here), edge importance is reversed. <b>Panel...
<p><b>Left column:</b> 3-state diagram with accelerated/decelerated edges labeled 1 or <i>α</i> wher...
<p>The first seven cases correspond to the chain that has the third state observable (see <a href="h...
<p><b>Panel A</b> shows that the majority of the power comes from the observable edges (red dashed l...
<p>Top panel: This band diagram shows the rich sequence of transitions, from one nonequilibrium stat...
(A–C) Plots of τ and τ against in as is changed over six orders of magnitude. These changes in c...
<p>A: <i>γ</i> = 3 (gold), 1 (black), 0.7 (red), 0.51 (purple). B: <i>J</i><sub><i>c</i></sub> vs. <...
Arcs indicate transitions in the Markov chains—transition probabilities are omitted. The set of sour...
<p> is the closed state, is the open state, and is the inactivation state (n = 1…5); <i>k</i><sub>...
<p>– are the closed states; <i>O</i><sup>[Kv4.3]</sup> is the open state and – are the inactivation ...
<p>One of the states (black disk) is distinguishable from the rest (white disks). For example, the b...
(A-C) A line graph of RBH between stable-state pairs with varying κ (A: intermediate and high state;...
<p>A common transition leaving the compound state is shared by all single states although presenting...
<p>Due to rounding the presented transition probabilities may not sum perfectly to 1.00.</p
Scenario 3, states B (left) and C (right) of the simple reaction model: Normalised state classificat...
<p>For a low concentration ([ACh] = 0.5 <i>μ</i>M shown here), edge importance is reversed. <b>Panel...
<p><b>Left column:</b> 3-state diagram with accelerated/decelerated edges labeled 1 or <i>α</i> wher...
<p>The first seven cases correspond to the chain that has the third state observable (see <a href="h...
<p><b>Panel A</b> shows that the majority of the power comes from the observable edges (red dashed l...
<p>Top panel: This band diagram shows the rich sequence of transitions, from one nonequilibrium stat...
(A–C) Plots of τ and τ against in as is changed over six orders of magnitude. These changes in c...
<p>A: <i>γ</i> = 3 (gold), 1 (black), 0.7 (red), 0.51 (purple). B: <i>J</i><sub><i>c</i></sub> vs. <...
Arcs indicate transitions in the Markov chains—transition probabilities are omitted. The set of sour...
<p> is the closed state, is the open state, and is the inactivation state (n = 1…5); <i>k</i><sub>...
<p>– are the closed states; <i>O</i><sup>[Kv4.3]</sup> is the open state and – are the inactivation ...
<p>One of the states (black disk) is distinguishable from the rest (white disks). For example, the b...
(A-C) A line graph of RBH between stable-state pairs with varying κ (A: intermediate and high state;...
<p>A common transition leaving the compound state is shared by all single states although presenting...
<p>Due to rounding the presented transition probabilities may not sum perfectly to 1.00.</p
Scenario 3, states B (left) and C (right) of the simple reaction model: Normalised state classificat...
<p>For a low concentration ([ACh] = 0.5 <i>μ</i>M shown here), edge importance is reversed. <b>Panel...