Table S1. Demographic, clinical and pathological diagnosis of cases used in this study; Figure S1. Further characterization of novel monoclonal C9orf72 antibodies; Figure S2. Commercially available C9orf72 antibodies tested on C9orf72 knock-out brain tissue; Figure S3. C9orf72 double-label immunofluorescence and C9orf72 in situ hybridization; Figure S4. Immunofluorescence of human iPSC derived motor neurons; Figure S5. Immunoblot analysis of C9orf72 expression levels in frontal cortex. (PDF 14467 kb
Table S1. List of primary MSC samples. Table S2. List of primers. Table S3. List of antibodies. Figu...
Tau pathology observed with the Tau/pS422 antibody. a-f Immunofluorescence staining against hyperpho...
Plcg2 in situ hybridization on brain tissue. A) RNAScope for PLCG2, positive (PPIB) and negative (Da...
Absence of C9orf72 isoform I in the C9orf72 CRISPR targeted mice. a. Western blot of brain lysates f...
Levels of endogenous versus overexpressed C9orf72 in N2a and HEK293T cells. N2a (a) and HEK293T (b) ...
Figure S1. Neuropathology of case 3. The neuropathological study on brain sample from case 3 showed ...
In this file we provide raw data for characterization of antibodies used for NEUROD2 ChIP-Seq experi...
Table S1. Characteristics of the primary antibodies, immunohistochemistry conditions and expression ...
Table S1. Overview of mutations investigated during the maturation process. Table S2. Names and sequ...
Antibodies used for immunofluorescence, immunohistochemistry, and western blotting. (PDF 48 kb
Expression profile of undifferentiated and differentiated (DD28) CTX0E16 cells. Undifferentiated CTX...
Table S1. Scoring of inflammatory infiltrates. Each level of the spinal cord was examined for the nu...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Undigested P3 fraction assessed with CP13 and PHF1 antibodies. A schematic of antibody epitopes is p...
Figure S6. Validation of Knockdown Efficiency of shRNAs and Inhibitory Effect of CREST on Transcript...
Table S1. List of primary MSC samples. Table S2. List of primers. Table S3. List of antibodies. Figu...
Tau pathology observed with the Tau/pS422 antibody. a-f Immunofluorescence staining against hyperpho...
Plcg2 in situ hybridization on brain tissue. A) RNAScope for PLCG2, positive (PPIB) and negative (Da...
Absence of C9orf72 isoform I in the C9orf72 CRISPR targeted mice. a. Western blot of brain lysates f...
Levels of endogenous versus overexpressed C9orf72 in N2a and HEK293T cells. N2a (a) and HEK293T (b) ...
Figure S1. Neuropathology of case 3. The neuropathological study on brain sample from case 3 showed ...
In this file we provide raw data for characterization of antibodies used for NEUROD2 ChIP-Seq experi...
Table S1. Characteristics of the primary antibodies, immunohistochemistry conditions and expression ...
Table S1. Overview of mutations investigated during the maturation process. Table S2. Names and sequ...
Antibodies used for immunofluorescence, immunohistochemistry, and western blotting. (PDF 48 kb
Expression profile of undifferentiated and differentiated (DD28) CTX0E16 cells. Undifferentiated CTX...
Table S1. Scoring of inflammatory infiltrates. Each level of the spinal cord was examined for the nu...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Undigested P3 fraction assessed with CP13 and PHF1 antibodies. A schematic of antibody epitopes is p...
Figure S6. Validation of Knockdown Efficiency of shRNAs and Inhibitory Effect of CREST on Transcript...
Table S1. List of primary MSC samples. Table S2. List of primers. Table S3. List of antibodies. Figu...
Tau pathology observed with the Tau/pS422 antibody. a-f Immunofluorescence staining against hyperpho...
Plcg2 in situ hybridization on brain tissue. A) RNAScope for PLCG2, positive (PPIB) and negative (Da...