Additional file 9: Figure S20. of The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition

Undigested P3 fraction assessed with CP13 and PHF1 antibodies. A schematic of antibody epitopes is presented. Blot represents P3 fraction from 3 animals of classes I, II and IV. Class I mice at ages 587, 662, and 646 days left to right, class II animals at ages 735, 592, and 658 days left to right, and class IV mice at ages 530, 466, and 639 days left to right. For both blots, 5 μg of total protein was loaded on the gel. Antibody: CP13 (1/500) and PHF1 (1/500). (TIFF 199 kb