Sepsis research has had relatively limited therapeutic success so far. In their recent study, Kobzik and colleagues (Joachim etal, ) identify novel drug-sensitive pathways in sepsis, derived exclusively from patient data. Their strategy is based on the analysis of a naturally sepsis-resistant population (pre-puberty children) and on the implementation of a novel-rich Pathway Drug Network, constructed from human gene expression data enriched in drug-pathway-gene clusters
BackgroundSepsis, a leading cause of morbidity and mortality, is not a homogeneous disease but rathe...
The design of clinical immunology studies in sepsis presents several fundamental challenges to impro...
For nearly a decade, our research group has had the privilege of developing and mining a multi-cente...
Sepsis research has had relatively limited therapeutic success so far. In their recent study, Kobzik...
Attempts to develop drugs that address sepsis based on leads developed in animal models have failed....
Sepsis causes extensive morbidity and mortality in children worldwide. Prompt recognition and timely...
Globally, various researchers have suggested that sepsis is one of the most prominent causes of infa...
Sepsis causes extensive morbidity and mortality in children worldwide. Prompt recognition and timely...
Models of sepsis have been instructive in understanding the sequence of events in animals and, to an...
Sepsis remains a major public health problem with no major therapeutic advances over the last severa...
The early diagnosis and appropriate stratification of sepsis continues to be one of the most importa...
Junting Yang,1,* Shunwen Zhang,1,2,* Jie Zhang,3 Jiangtao Dong,3 Jiangdong Wu,1 Le Zhang,1 Peng Guo...
Sepsis has over the years proven a considerable challenge to physicians and researchers. Numerous ph...
Background: Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also impli...
BACKGROUND The role of primary immunodeficiencies (PID) in susceptibility to sepsis remains unkno...
BackgroundSepsis, a leading cause of morbidity and mortality, is not a homogeneous disease but rathe...
The design of clinical immunology studies in sepsis presents several fundamental challenges to impro...
For nearly a decade, our research group has had the privilege of developing and mining a multi-cente...
Sepsis research has had relatively limited therapeutic success so far. In their recent study, Kobzik...
Attempts to develop drugs that address sepsis based on leads developed in animal models have failed....
Sepsis causes extensive morbidity and mortality in children worldwide. Prompt recognition and timely...
Globally, various researchers have suggested that sepsis is one of the most prominent causes of infa...
Sepsis causes extensive morbidity and mortality in children worldwide. Prompt recognition and timely...
Models of sepsis have been instructive in understanding the sequence of events in animals and, to an...
Sepsis remains a major public health problem with no major therapeutic advances over the last severa...
The early diagnosis and appropriate stratification of sepsis continues to be one of the most importa...
Junting Yang,1,* Shunwen Zhang,1,2,* Jie Zhang,3 Jiangtao Dong,3 Jiangdong Wu,1 Le Zhang,1 Peng Guo...
Sepsis has over the years proven a considerable challenge to physicians and researchers. Numerous ph...
Background: Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also impli...
BACKGROUND The role of primary immunodeficiencies (PID) in susceptibility to sepsis remains unkno...
BackgroundSepsis, a leading cause of morbidity and mortality, is not a homogeneous disease but rathe...
The design of clinical immunology studies in sepsis presents several fundamental challenges to impro...
For nearly a decade, our research group has had the privilege of developing and mining a multi-cente...
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