Data-intensive science collaborations increasingly provision dedicated network circuits to share and exchange datasets securely at high speed, leveraging national-footprint research fabrics such as ESnet or I2/AL2S. This talk first gives an overview of new features to automate circuit interconnection of science resources across campuses and in network cloud testbeds, such as GENI (e.g., ExoGENI) and NSFCloud (e.g., Chameleon). Taken together, these tools can enable science teams to deploy secure bandwidth-provisioned virtual science networks that link multiple campuses and/or virtual testbed slices, with integrated in-network processing on virtual cloud servers. Next, we outline a software framework to address security issues arisin...