Model-based reliability analysis and assessment methods rely on models, which are assumed to be precise, to predict reliability. In practice, however, the precision of the model cannot be guaranteed due to the presence of epistemic uncertainty. In this paper, a new reliability metric, called belief reliability, is defined to explicitly account for epistemic uncertainty in model-based reliability analysis and assessment. A new method is developed to explicitly quantify epistemic uncertainty by measuring the effectiveness of the engineering analysis and assessment activities related to reliability. To evaluate belief reliability, an integrated framework is presented where the contributions of design margin, aleatory uncertainty, and epistemic...