Additional file 1: of 6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice
- Andreas Margraf (5162732)
- Jan Herter (5162738)
- Katharina Kühne (5162729)
- Anika Stadtmann (5162726)
- Thomas Ermert (5162741)
- Manuel Wenk (5162735)
- Melanie Meersch (543833)
- Hugo Van Aken (67265)
- Alexander Zarbock (92952)
- Jan Rossaint (306962)
Publication date
May 2018
DOIAbstract
Figure S1. Effects of HES 130/0.4 on hyaluronidase plasma levels during systemic and pulmonary inflammation. (A) Wild-type mice underwent sham or CLP operation (n = 8). Sixty minutes after the procedure, mice received 20 ml/kg Isolyte® (Iso) or HES 130/0.4 (HES) as an infusion over 1 h. The hyaluronidase plasma levels were analyzed 4, 8, and 24 h after the operation. (B) Wild-type mice were exposed to nebulized saline or LPS (n = 8). Sixty minutes after the procedure, mice received 20 ml/kg Isolyte® (Iso) or HES 130/0.4 (HES) as an infusion over 1 h. The hyaluronidase plasma levels were analyzed 4, 8, and 24 h after the procedure. Mean ± SEM. * p < 0.05. (PDF 606 kb
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