<p><b>A</b>: Effect of H<sub>2</sub>O<sub>2</sub> on cell viability. Cytotoxicity was measured using an LDH assay. n = 3. <b>B</b>: Effect of propofol (PR) on cell viability. Scale bar, 200 μm. <b>C</b>: Quantitative analysis of PR-induced cytotoxicity in H9c2 cells. n = 3. <b>D</b>: Diagram of the scheme of propofol (PR) and H<sub>2</sub>O<sub>2</sub> treatment. <b>E</b>: Effect of PR on cell viability under oxidative stress conditions. Arrows, dead cells; arrowheads, surviving cells. Scale bar, 250 μm. <b>F</b>: Quantification of dead H9c2 cells. n = 3. The data are expressed as mean ± SEM. <b>G</b>: TUNEL staining. Arrowheads, TUNEL-positive cells. Scale bar, 200 μm. <b>H</b>: Quantification of TUNEL-positive cells. n = 3. The data are e...
<p><b>A</b>: mRNA expression profile for HO-1. n = 3. The data are expressed as mean ± SEM. <b>B</b>...
<div><p>Oxidative stress contributes to myocardial ischemia-reperfusion injury, which causes cardiom...
Intro: Propofol, an IV anesthetic that activates cardioprotective signaling mechanisms against I/R i...
<p>SH-SY5Y cells were exposed to the indicated concentrations (12.5, 25, 50, 100, or 150 μM) of prop...
<p>(A) OCR and (B) ECAR of P29, its cybrid cells, and ρ0P29 cells. (C and D) P29, its cybrid cells, ...
minutes, HK2 cells were exposed to 8 mM H2O2 for 4 hours. Cell death was assessed by measuring the p...
<p>(A) SH-SY5Y cells were exposed to the indicated concentrations (12.5, 25, 50, 100, or 150 μM) of ...
<p>(A) Production of ROS, as measured by 2,7-dichlorodihydrofluorescein diacetate (H2-DCFDA) (left p...
Objective: To test the hypothesis that oxygen free radicals can potentiate TNF-α cellular toxicity, ...
<p>OCR (A, C, and E) and ECAR (B, D, and F) in SH-SY5Y cells or P29 cells exposed to the indicated c...
<p>(a-j) Detection of apoptosis with Annexin V-FITC and propidium iodide staining. Cells were precon...
<p>P29 and ρ0P29 cells lacking mtDNA were exposed to the indicated concentrations (25, 50 or 100 μM)...
<p>(A) Apoptotic cells in control group, Propofol group, TG group and Propofol+TG group were analyze...
<p>Levels of caspase-3/7 activity and cell death in SH-SY5Y cells treated with propofol and mitochon...
<p><b>A-D</b>: Effect of Nrf2, HO-1, Nqo-1 or scramble siRNA on propofol-induced cytoprotection, aft...
<p><b>A</b>: mRNA expression profile for HO-1. n = 3. The data are expressed as mean ± SEM. <b>B</b>...
<div><p>Oxidative stress contributes to myocardial ischemia-reperfusion injury, which causes cardiom...
Intro: Propofol, an IV anesthetic that activates cardioprotective signaling mechanisms against I/R i...
<p>SH-SY5Y cells were exposed to the indicated concentrations (12.5, 25, 50, 100, or 150 μM) of prop...
<p>(A) OCR and (B) ECAR of P29, its cybrid cells, and ρ0P29 cells. (C and D) P29, its cybrid cells, ...
minutes, HK2 cells were exposed to 8 mM H2O2 for 4 hours. Cell death was assessed by measuring the p...
<p>(A) SH-SY5Y cells were exposed to the indicated concentrations (12.5, 25, 50, 100, or 150 μM) of ...
<p>(A) Production of ROS, as measured by 2,7-dichlorodihydrofluorescein diacetate (H2-DCFDA) (left p...
Objective: To test the hypothesis that oxygen free radicals can potentiate TNF-α cellular toxicity, ...
<p>OCR (A, C, and E) and ECAR (B, D, and F) in SH-SY5Y cells or P29 cells exposed to the indicated c...
<p>(a-j) Detection of apoptosis with Annexin V-FITC and propidium iodide staining. Cells were precon...
<p>P29 and ρ0P29 cells lacking mtDNA were exposed to the indicated concentrations (25, 50 or 100 μM)...
<p>(A) Apoptotic cells in control group, Propofol group, TG group and Propofol+TG group were analyze...
<p>Levels of caspase-3/7 activity and cell death in SH-SY5Y cells treated with propofol and mitochon...
<p><b>A-D</b>: Effect of Nrf2, HO-1, Nqo-1 or scramble siRNA on propofol-induced cytoprotection, aft...
<p><b>A</b>: mRNA expression profile for HO-1. n = 3. The data are expressed as mean ± SEM. <b>B</b>...
<div><p>Oxidative stress contributes to myocardial ischemia-reperfusion injury, which causes cardiom...
Intro: Propofol, an IV anesthetic that activates cardioprotective signaling mechanisms against I/R i...