Risk Factor for Metastasis in StageⅤOral Squamous Cell Carcinoma

目的 探讨口腔癌levelⅤ转移的影响因素.方法 306例伴有颈淋巴结转移的口腔癌患者,均接受根治性颈清或改良根治性颈清.应用logistic回归分析levelⅤ转移的风险因素,分析变量包括年龄、性别、原发灶部位、生长方式、T分期、病理分级、LevelⅠ~Ⅳ转移状态.结果 LevelⅤ转移19侧(5.99%,19/317).多因素分析结果表明只有levelⅣ转移、前四区阳性淋巴结个数≥4与levelⅤ转移有关联.结论 levelⅠ~Ⅳ淋巴结的转移状态是levelⅤ转移风险因素之一.Objective To investigate the risk factor for metastasis in stage Ⅴoral squamous cell carcinoma.Methods 306 patients with oral squamous cell carcinoma and positive neck nodes received radical neck dissection or modified radical neck dissection.Logistic regression was performed to identify the risk factors for metastasis in stage Ⅴoral squamous cell carcinoma.The variables included age ,gender,primary site,growth type,T classification,tumor differentiation,metastasis status in stageⅠ~Ⅳ.Results StageⅤhad 19 cases of neck (5.99%,19/317)metastasis.Multivariate analysis confirmed that only stage Ⅳ in-volvement,and number of positive lymph node (≥4 nodes)were associated with metastasis in stageⅤ.Conclusion The metasta-sis status in stageⅠ~Ⅳis considered as one of the risk factors for stageⅤmetastasis.1131-1333