Structural failure investigations can be strongly influenced by high levels of uncertainty in modelling parameters, particularly in the case of historical constructions. This suggests forensic analysts to perform probabilistic simulations, allowing a risk-informed diagnosis and prognosis of structural failures. In this study, a failure investigation methodology including uncertainty characterisation, modelling and propagation is presented and applied to a historic piperno stone balcony, the collapse of which caused four casualties. High uncertainty in physical and mechanical properties of piperno stone, which has been widely used for a long time in the architectural heritage of Naples and Southern Italy, motivated stochastic finite element ...