Additional file 2: of The DNA methylation profile of liver tumors in C3H mice and identification of differentially methylated regions involved in the regulation of tumorigenic genes

Figure S1. Scatter plots for sample pairs. Scatter plots of % methylation values for each pair in normal tissues (n = 3) and tumor tissues (n = 3) were obtained using methylKit. Numbers on upper right corner denote pair-wise Pearson’s correlation scores. The histograms on the diagonal are methylation distribution of CpG sites for each sample. Figure S2/. Expression levels of Mst1r, Slpi and Extl1 in tumor tissues with (n = 6) and without (n = 5) Ha-ras mutation. Figure S3. Hepa1-6 cells show lower expression of Dnmts compared to Hepa1c1c7. cDNA was prepared from Hepa1c1c7 cells and Hepa1-6 cells and the expression was measured by real-time PCR (n = 3). All genes were normalized to the expression of rRNA.. *** p < 0.001. (PPTX 296 kb