Metaphase images and quantification.

<p>FSS dramatically increases the fraction of MOSE-E cells with near-tetraploid chromosome numbers. (<b>A</b>) Examples of metaphase spreads with near-diploid (left) and near-tetraploid (right) range. (<b>B</b>) Chromosome counts in individual metaphase spreads from the control (black) and FSS-exposed adherent (gray) MOSE-E cells. Upon exposure to FSS, the fraction of near tetraploid cells increased to 76% ± 2.4% compared to 31% ± 5.0% in the control population (<i>χ</i>², p = 0.013).