Karyotype changes in T cells as assessed from metaphase chromosomes.

A. Types of karyotype changes detected in the analysed cells, charted by the percentage of cells where the category’s events were found. See also S4 Table. B. An example of the derivative chromosomes found in the D+H karyotyping samples (45, XY, der(13;22)(q10;q10)); the recombined chromosomes 13 and 22, and the derivative chromosome enlarged, with an arrow denoting the derivative chromosome. C. Distribution of total structural changes across the chromosomes containing rDNA repeats.