Pathogenic responses are improved in transplanted mice that received DC/CCL21.

<p><b>A. Ova specific responses. BMT m</b>ice were assessed on day 50 for absolute numbers OVA–specific T cells. <b>B. Bacterial clearance</b>. To determine bacterial clearance, livers from BMT mice were assessed for bacterial clearance on day 50. Each group had 3–5 mice; this experiment was done with three replicates. <b>C. Viral clearance</b>. Spleens from BMT mice were assessed for viral clearance on day 43 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0193461#pone.0193461.ref045" target="_blank">45</a>]. Each group had 3–5 mice; this experiment was reproduced two times with similar results. <b>D. Anti-tumor responses</b>. BMT mice were injected on day 42 with tumor cells; survival was monitored weekly. There were at least 4 mice per group. This is representative of two experiments. P = 0.0009 utilizing log rank Mantel-Cox test.