Histamine metabolism influences blood vessel branching in zebrafish mutants-7

Hite bars) 3-dpa regenerates. (B, C) Whole-mount in situ hybridization for egr-1 on wild-type (B) and (C) 3-dpa regenerates showed decreased expression of egr-1 in fish. Arrows, egr-1 RNA signal. (D) The egr-1 expression in mutants was upregulated more than 2.5-fold by 1 mM histamine and 10 μM SKF91488 but was downregulated by 300 μM urocanic acid. The expression level was determined by QPCR and normalized by the expression level of the β-actin gene.<p><b>Copyright information:</b></p><p>Taken from "Histamine metabolism influences blood vessel branching in zebrafish mutants"</p><p>http://www.biomedcentral.com/1471-213X/8/31</p><p>BMC Developmental Biology 2008;8():31-31.</p><p>Published online 25 Mar 2008</p><p>PMCID:PMC2291033.</p><p>