Ol samples obtained before DSS exposure began, at the end of each 5 day cycle of DSS administration, and after 16 days of recovery prior to beginning the next DSS cycle for wild type (n = 49–50 mice for days 0, 47, and 62, and n = 9 – 10 for the remaining time points) and RAG-2mice (n = 14). Mean cytokine concentrations per 100 mg stool are shown. Error bars are omitted for clarity. * indicates values significantly different from pre-treatment level for a given genotype. # indicates values significantly different (p ≤ 0.02) in wild type vs. RAG-2mice.<p><b>Copyright information:</b></p><p>Taken from "Treatment of experimental colitis in mice with LMP-420, an inhibitor of TNF transcription"</p><p>http://www.journal-inflammation.com/content/5...
<p>WT mice were infected with H1N1 100 pfu i.n. and on day 7 challenged with 5×10<sup>7</sup> cfu cM...
<p>Sections of colon from mock- or S. Typhimurium-infected wild-type (C57BL/6) and PPARγVillinCre<su...
Background: Current understanding of the onset of inflammatory bowel diseases relies heavily on data...
Ction, mice were challenged i.p. with a lethal dose of 0.5 mg LPS then euthanized 2 hrs. later for m...
drinking water, followed by 16 days of plain water. LMP-420 therapy was given parenterally (i.p.) or...
Treatment with i.p. (panel A) or oral (panel C) LMP-420 at the indicated doses. LMP-420 doses of 5 m...
Icited macrophages (MΦ) (n = 3) 24 hrs after exposure to LPS. The IC50 threshold (the concentration ...
Icited macrophages (MΦ) (n = 3) 24 hrs after exposure to LPS. The IC50 threshold (the concentration ...
DSS-induced colitis is a common in vivo model for IBD. Our study employed acute dosing of DSS from D...
<p>Mice were challenged with 2.5% dextran sodium sulfate in the drinking water for 7 days. Disease a...
a<p>In two independent studies, serum concentrations of 23 cytokines were determined by multiplex te...
<p>Disease activity index (DAI), colon histological damage score and clinical evaluation of DSS trea...
<p><b>A.</b> Schema of a DSS treatment experiment. DSS at the concentration of 3% was administered i...
<p>Protective effect of intra-peritoneal administration of LAB-treated BMDCs on acute TNBS-induced c...
<div><p>(A) Severity of colitis in DSS-treated animals. Clinical outcome of colitis was recorded in ...
<p>WT mice were infected with H1N1 100 pfu i.n. and on day 7 challenged with 5×10<sup>7</sup> cfu cM...
<p>Sections of colon from mock- or S. Typhimurium-infected wild-type (C57BL/6) and PPARγVillinCre<su...
Background: Current understanding of the onset of inflammatory bowel diseases relies heavily on data...
Ction, mice were challenged i.p. with a lethal dose of 0.5 mg LPS then euthanized 2 hrs. later for m...
drinking water, followed by 16 days of plain water. LMP-420 therapy was given parenterally (i.p.) or...
Treatment with i.p. (panel A) or oral (panel C) LMP-420 at the indicated doses. LMP-420 doses of 5 m...
Icited macrophages (MΦ) (n = 3) 24 hrs after exposure to LPS. The IC50 threshold (the concentration ...
Icited macrophages (MΦ) (n = 3) 24 hrs after exposure to LPS. The IC50 threshold (the concentration ...
DSS-induced colitis is a common in vivo model for IBD. Our study employed acute dosing of DSS from D...
<p>Mice were challenged with 2.5% dextran sodium sulfate in the drinking water for 7 days. Disease a...
a<p>In two independent studies, serum concentrations of 23 cytokines were determined by multiplex te...
<p>Disease activity index (DAI), colon histological damage score and clinical evaluation of DSS trea...
<p><b>A.</b> Schema of a DSS treatment experiment. DSS at the concentration of 3% was administered i...
<p>Protective effect of intra-peritoneal administration of LAB-treated BMDCs on acute TNBS-induced c...
<div><p>(A) Severity of colitis in DSS-treated animals. Clinical outcome of colitis was recorded in ...
<p>WT mice were infected with H1N1 100 pfu i.n. and on day 7 challenged with 5×10<sup>7</sup> cfu cM...
<p>Sections of colon from mock- or S. Typhimurium-infected wild-type (C57BL/6) and PPARγVillinCre<su...
Background: Current understanding of the onset of inflammatory bowel diseases relies heavily on data...