(B) Quantification of lesion size relative to the hippocampus over a series of three to six sections per animal ( = 5 per experimental group). Data are represented as mean ± SEM (error bars), with statistical significance denoted as **, P < 0.001. Bar, 200 μm.<p><b>Copyright information:</b></p><p>Taken from "Prion protein attenuates excitotoxicity by inhibiting NMDA receptors"</p><p></p><p>The Journal of Cell Biology 2008;181(3):551-565.</p><p>Published online 5 May 2008</p><p>PMCID:PMC2364707.</p><p></p
<p>Immunofluorescence analysis of nestin, DCX, BetaIII-Tubulin and GFAP markers in differentiated NS...
<p>(Anterior-posterior levels based on Bregma are shown in schematics; scale for all photomicrograph...
In PrP-null neurons, NMDA-mediated mEPSCs were observed to be larger and showed prolonged decay time...
3, 0.6, and 1.0 mM NMDA followed by 24-h recovery. Cells were stained with trypan blue (dark blue) a...
<p>(<b>A</b>) The gene expression levels of 3 neuronal markers (NEFL, NEM and SNAP25) in control and...
<p>(A) Representative images of Gallyas silver-stained hippocampi from adeno-associated virus seroty...
<p>A–E: Representative GFAP labelling in control (A), light damage (B), 7 d PBM (C), 10 d saffron (D...
<p>(<b>A</b>) The expression levels of microglia (AIF1) and astrocyte (GFAP) cell markers determined...
α-Actin expression was used as a loading control. (B) NMDAR subunit surface expression as visualized...
(A) Western blotting of 20 μL 1% (w/v) crude M1000 brain homogenates (cM1000) from 30%, 50%, 70%, an...
<p>Photomicrographs of toluidine blue-stained hippocampal neurons in CA3 (A-D), CA4 (G–J), and the u...
<p>(<b>A</b>) A schematic diagram of the statistics area in the hippocampus. MAP2 immunoreactivity (...
Profiles of vacuolation scores of animals inoculated with samples containing A. Shaking-propagated M...
(A) Western blotting of 20μL of preparations obtained following immuno-precipitation of total PrP sp...
<p>Two-way ANOVA revealed a significant interaction between drug treatment (DFMO vs vehicle) and inj...
<p>Immunofluorescence analysis of nestin, DCX, BetaIII-Tubulin and GFAP markers in differentiated NS...
<p>(Anterior-posterior levels based on Bregma are shown in schematics; scale for all photomicrograph...
In PrP-null neurons, NMDA-mediated mEPSCs were observed to be larger and showed prolonged decay time...
3, 0.6, and 1.0 mM NMDA followed by 24-h recovery. Cells were stained with trypan blue (dark blue) a...
<p>(<b>A</b>) The gene expression levels of 3 neuronal markers (NEFL, NEM and SNAP25) in control and...
<p>(A) Representative images of Gallyas silver-stained hippocampi from adeno-associated virus seroty...
<p>A–E: Representative GFAP labelling in control (A), light damage (B), 7 d PBM (C), 10 d saffron (D...
<p>(<b>A</b>) The expression levels of microglia (AIF1) and astrocyte (GFAP) cell markers determined...
α-Actin expression was used as a loading control. (B) NMDAR subunit surface expression as visualized...
(A) Western blotting of 20 μL 1% (w/v) crude M1000 brain homogenates (cM1000) from 30%, 50%, 70%, an...
<p>Photomicrographs of toluidine blue-stained hippocampal neurons in CA3 (A-D), CA4 (G–J), and the u...
<p>(<b>A</b>) A schematic diagram of the statistics area in the hippocampus. MAP2 immunoreactivity (...
Profiles of vacuolation scores of animals inoculated with samples containing A. Shaking-propagated M...
(A) Western blotting of 20μL of preparations obtained following immuno-precipitation of total PrP sp...
<p>Two-way ANOVA revealed a significant interaction between drug treatment (DFMO vs vehicle) and inj...
<p>Immunofluorescence analysis of nestin, DCX, BetaIII-Tubulin and GFAP markers in differentiated NS...
<p>(Anterior-posterior levels based on Bregma are shown in schematics; scale for all photomicrograph...
In PrP-null neurons, NMDA-mediated mEPSCs were observed to be larger and showed prolonged decay time...