Ks were calculated with the software K-estimator []. The genomes were analyzed in windows of 200 nt and a shift of the window of 100 nt in each step. The scaled protein-coding region of the FMDV genome is indicated in the abscissa [,]. The confidence intervals (dotted horizontal line) were calculated by k-estimator using Monte Carlo simulations []. A) Ka ratios. B) Ks ratios. C) Comparison of Ka and Ks ratios for RAp45.<p><b>Copyright information:</b></p><p>Taken from "Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection"</p><p>http://www.biomedcentral.com/1471-2148/8/207</p><p>BMC Evolutionary Biology 2008;8():207-207.</p><p>Published online 17 Jul 2008</p><p>PMCID:PM...
<p>(A) The frequencies of proviral genomes in different Hamming classes at various times (generation...
Motivation: Modern genomes and their statistical properties reflect the series of steps by which the...
a<p>BHK-21 cell monolayers were infected with VSV, FMDV or EMCV at the indicated MOI in the absence ...
Of residues as in []) of molecular clones obtained from populations at passage 1 (left) or passage 2...
Igher than 75 are indicated with numbers; values between 60 and 74 are indicated in parenthesis. Eac...
Of residues as in []) of molecular clones obtained from populations at passage 1 (left) or passage 2...
consensus nucleotide sequences of populations derived from biological clone C-S8c1 (p50, p100, p143,...
En arbitrarily the value AD = 0.0. The populations analyzed in A and B are those described in Figure...
I. passages (1 to 5 PFU/cell). Drug concentrations during the infections are indicated on the corres...
a<p>The viral populations are those described in <a href="http://www.plosone.org/article/info:doi/10...
The ratio between these two values is a measure for the degree by which context-dependent codon choi...
<p>For 28 nidoviruses representing species diversity, absolute sizes of 3′ORFs (A), ORF1a (B), and O...
a<p>The consensus sequence of the entire viral genome was determined for FMDV populations V19–4A and...
[Methods] This submission contains all the R code used for numerical predictions and simulations pre...
<p>Population genetic parameters estimated from segregating sites within the MdBV proviral genome (a...
<p>(A) The frequencies of proviral genomes in different Hamming classes at various times (generation...
Motivation: Modern genomes and their statistical properties reflect the series of steps by which the...
a<p>BHK-21 cell monolayers were infected with VSV, FMDV or EMCV at the indicated MOI in the absence ...
Of residues as in []) of molecular clones obtained from populations at passage 1 (left) or passage 2...
Igher than 75 are indicated with numbers; values between 60 and 74 are indicated in parenthesis. Eac...
Of residues as in []) of molecular clones obtained from populations at passage 1 (left) or passage 2...
consensus nucleotide sequences of populations derived from biological clone C-S8c1 (p50, p100, p143,...
En arbitrarily the value AD = 0.0. The populations analyzed in A and B are those described in Figure...
I. passages (1 to 5 PFU/cell). Drug concentrations during the infections are indicated on the corres...
a<p>The viral populations are those described in <a href="http://www.plosone.org/article/info:doi/10...
The ratio between these two values is a measure for the degree by which context-dependent codon choi...
<p>For 28 nidoviruses representing species diversity, absolute sizes of 3′ORFs (A), ORF1a (B), and O...
a<p>The consensus sequence of the entire viral genome was determined for FMDV populations V19–4A and...
[Methods] This submission contains all the R code used for numerical predictions and simulations pre...
<p>Population genetic parameters estimated from segregating sites within the MdBV proviral genome (a...
<p>(A) The frequencies of proviral genomes in different Hamming classes at various times (generation...
Motivation: Modern genomes and their statistical properties reflect the series of steps by which the...
a<p>BHK-21 cell monolayers were infected with VSV, FMDV or EMCV at the indicated MOI in the absence ...