<p>Binding affinity to various ligands was compared using the quenching value (Q), as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0029710#pone-0029710-g005" target="_blank">Figure 5</a>. Bars represent the means of three independent replicates, and error bars indicate standard error.</p
<p>Molecules identified in this study. Binding affinity data at three AR subtypes are presented in <...
<p>Bars indicate the mean binding inhibition of 3D7 (A) or FCR3 (B) <i>Plasmodium falciparum</i> inf...
(a) Experimental pIC50 versus calculated binding free energy ΔG. (b) ΔpIC50 and ΔΔG are differences ...
<p>Binding affinity to various ligands was compared among the three OBPs using the quenching value (...
<p>Box plots show distributions of differences in binding affinity for small molecules grouped by eq...
a<p><i>K</i><sub>D</sub> values as reported in ref. <a href="http://www.plosone.org/article/info:doi...
<p>For each test case with more than two mutations, we plotted the top binding scores of CADDSuite, ...
<p>Sequence identity was measured on three levels: (a,d) Full sequence, (b,e) sequence of the domain...
<p>Fold change was determined for RNA binding by comparing each mutant K<sub>D</sub> value to wild-t...
<p>Shown is a scatter plot of the experimentally measured relative binding affinities of double and ...
<p>‘’ is the specific binding energy of the highest affinity site as determined by the intercept of ...
To identify the major determinants of the DNA binding specificity of nuclear transcription factors, ...
<p>Best scoring results for docking of true, foreign and non-binders to apo (first row), 5 morphing ...
<p>(A) The reactivity of the protein binders (wild-type and mutant clones) against EGFR (black) and ...
<p>(A) Colors code the degree of tolerance of appended groups: pharmacophores (minimum structural re...
<p>Molecules identified in this study. Binding affinity data at three AR subtypes are presented in <...
<p>Bars indicate the mean binding inhibition of 3D7 (A) or FCR3 (B) <i>Plasmodium falciparum</i> inf...
(a) Experimental pIC50 versus calculated binding free energy ΔG. (b) ΔpIC50 and ΔΔG are differences ...
<p>Binding affinity to various ligands was compared among the three OBPs using the quenching value (...
<p>Box plots show distributions of differences in binding affinity for small molecules grouped by eq...
a<p><i>K</i><sub>D</sub> values as reported in ref. <a href="http://www.plosone.org/article/info:doi...
<p>For each test case with more than two mutations, we plotted the top binding scores of CADDSuite, ...
<p>Sequence identity was measured on three levels: (a,d) Full sequence, (b,e) sequence of the domain...
<p>Fold change was determined for RNA binding by comparing each mutant K<sub>D</sub> value to wild-t...
<p>Shown is a scatter plot of the experimentally measured relative binding affinities of double and ...
<p>‘’ is the specific binding energy of the highest affinity site as determined by the intercept of ...
To identify the major determinants of the DNA binding specificity of nuclear transcription factors, ...
<p>Best scoring results for docking of true, foreign and non-binders to apo (first row), 5 morphing ...
<p>(A) The reactivity of the protein binders (wild-type and mutant clones) against EGFR (black) and ...
<p>(A) Colors code the degree of tolerance of appended groups: pharmacophores (minimum structural re...
<p>Molecules identified in this study. Binding affinity data at three AR subtypes are presented in <...
<p>Bars indicate the mean binding inhibition of 3D7 (A) or FCR3 (B) <i>Plasmodium falciparum</i> inf...
(a) Experimental pIC50 versus calculated binding free energy ΔG. (b) ΔpIC50 and ΔΔG are differences ...