MAF and within-gene pairwise LD distributions in actual sequence data.

<p>Distributions of MAFs (Panel A) and within-gene pairwise LD (Panel B) for biallelic variants in six candidate genes for dilated cardiomyopathy. Pairwise LD was measured by the correlation coefficient (<i>r</i>) between major/minor alleles for variants within the same gene. These distributions were estimated from 184 Coriell samples of European descent. The vertical dashed line in Panel B indicates <i>r</i> = 0.