Z-score calculations show a variable correlation between the methylation status of RBP3 gene CpG sites.

<p>Z-score of correlation between methylated sites for <i>RPB3</i> in human cell lines HEK293 and Y79. <i>A</i>, Z-score of CpG site pairs (<i>RPB3</i> CpG sites 314–737, and 777–957 bp downstream of the TSS, which were amplified as 2 separate PCR products). There was no Z-score if one site was extremely hypermethylated or hypomethylated. Z-scores ranged from 6 (red) to −2 (dark blue). <i>B</i>, Z-score as function of distance between CpG site pairs in base pairs (bp). Magenta circles represent smoothed values within 9-point smoothing window.