The transcription of I-molecules dominates for a transient signal (K_deg,T = 1.0 min⁻¹ for Model 1 and K_deg,T = 0.1 min⁻¹ for Model 2).

<p>(A) Time course trajectories for molecule I obtained by solution of the Model 1 equations using a mean field ODE solver (red curve) and ten times using the Gillespie Algorithm (10 blue curves). (B) Time course trajectories for molecule A obtained by solution of the Model 1 equations using a mean field ODE solver (red curve) and ten times using the Gillespie Algorithm (10 blue curves). (C) Histogram for molecule I obtained by solving the Model 1 equations using the Gillespie Algorithm 1000 times and recording the number of molecules at 2000 min. (D) Histogram for molecule A obtained by solving the Model 1 equations using the Gillespie Algorithm 1000 times and recording the number of molecules at 2000 min. (E) Histogram for molecule I obtained by solving the Model 2 equations using the Gillespie Algorithm 1000 times and recording the number of molecules at 2000 min. (F) Histogram for molecule A obtained by solving the Model 2 equations using the Gillespie Algorithm 1000 times and recording the number of molecules at 2000 min. Parameters for Model 1 were obtained from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033018#pone-0033018-t001" target="_blank">Table 1</a> and parameters for Model 2 were obtained from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033018#pone.0033018.s009" target="_blank">Table S2</a>.