CD8⁺ T cells in spleen and mediastinal lymph nodes (MeLN).

<p>Flow cytometry graphs showing the cell populations in spleen from one representative mouse from each group (A). Numbers given in the graphs are per cent cells out of all lymphocytes. The fraction (B) and total cell count (C) of CD8⁺ T cells in spleen and MeLN of <i>Apoe^−/−</i>, <i>Apoe^−/− Tap1^−/−</i> and <i>Tap1^−/−</i> mice. The cells were isolated from respective tissue, stained with fluorescent antibodies and analyzed by flow cytometry. As expected, the CD8⁺ T cell fraction was depressed in the mice lacking the <i>Tap1</i> gene. Each dot in the figure represents one mouse. ***<i>P</i><0.001.