CDL patients have a higher frequency of CD4⁺CD25^hiFoxP3^<b>+</b> cells in peripheral blood than AI.

<p>PBMCs from AI (n = 12) and CDL patients (n = 14) were stained for CD4, CD25 and either Foxp3, CD127, or GITR and analyzed by flow cytometry. <b>A</b>. Frequency of CD4⁺CD25^hiFoxp3⁺ cells. <b>B</b>. Frequency of CD4⁺CD25^hiCD127⁻ cells. <b>C</b>. Frequency of CD4⁺CD25^hiGITR⁺ cells. ***p<0.001, Mann-Whitney test. The median is represented by a horizontal line.