siRNA knockdown of p110α, Akt or mTOR phenocopies small molecule inhibitor treatments.
- Jeffrey J. Wallin (166819)
- Jane Guan (166826)
- Kyle A. Edgar (166833)
- Wei Zhou (24328)
- Ross Francis (166842)
- Anthony C. Torres (166847)
- Peter M. Haverty (166850)
- Jeffrey Eastham-Anderson (166851)
- Sabrina Arena (166853)
- Alberto Bardelli (163979)
- Sue Griffin (137485)
- John E. Goodall (166856)
- Kyla M. Grimshaw (166858)
- Klaus P. Hoeflich (166862)
- Christopher Torrance (166866)
- Marcia Belvin (166873)
- Lori S. Friedman (166879)
Publication date
May 2012
DOIAbstract
<p>(A) Knock-in cells (H1047R A) were transfected with the indicated siRNAs and plated in the 3-D culture assay for 5 days. (B) Assessment of siRNA knockdown by Western blot in the knock-in clone (H1047R A) 48 hours after transfection (NT = Non-targeting control siRNA).</p
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