<p><i>Hamp</i>, <i>Bmp6</i>, <i>Tmprss6</i> and <i>Id1</i> mRNA was determined by real-time PCR and expressed relative to β-actin mRNA. C: Control, Fe: Iron injection (200 mg/kg), ID: Iron-deficient diet, Bl: Bleeding (0.6 ml of blood once weekly for 3 weeks), Epo: Erythropoietin (50 U/day) administration for 4 days, WT: <i>Hjv</i>+/+ mice, KO: <i>Hjv</i>−/− mice. Asterisks indicate statistically significant difference (n = 4, p<0.05).</p
<p>qRT-PCR analysis of Tfr1 mRNA (<b>A</b>), Tfr2 mRNA (<b>B</b>), Id1 mRNA (<b>C</b>), Smad6 mRNA (...
<p>Transferrin saturation (TS, <b>A</b>) and non-heme liver (LIC, <b>B</b>) iron content were measur...
A-C: Liver Hamp, Id1 and Bmp6 mRNA content, expressed as ΔCT relative to Actb mRNA content. Male C57...
A-C: Liver Hamp, Id1 and Smad7 mRNA content in samples prepared from control C57BL/6 mice (C), EPO-t...
<div><h3>Introduction</h3><p>Hemojuvelin (Hjv) is a key component of the signaling cascade that regu...
INTRODUCTION: Hemojuvelin (Hjv) is a key component of the signaling cascade that regulates liver hep...
<p>Five male wild type (WT) and five <i>Hjv-</i>/- mice at ∼10-weeks old were used for the studies. ...
<p>C57BL/6 wild type mice were fed with iron replete diet (IR), or iron-rich diet for 3 days (Fe die...
<p>Tissues were taken from <i>Hbb</i><sup><i>th3/+</i></sup>, <i>RBC14</i> and <i>hbd</i> mice, and ...
<p>(A) Liver and spleen non-heme iron concentrations. (B) SI and TS%. (C–E) Liver mRNA levels of <i>...
<p>(A) Time course of liver and spleen non-heme iron concentrations after switching to an iron-defic...
<p>Iron was administered to male C57BL/6 mice as iron polyisomaltosate at 200 mg/kg, erythropoietin ...
<p>(A) Liver and spleen non-heme iron concentrations. (B) Serum iron concentration (SI, µg/dL) and p...
<p>Immunoblots of Hjv protein in liver crude membrane fractions. Panel A: Detection with primary ant...
<p>Iron levels were determined as described in <i>Methods</i>. Results are depicted graphically, wit...
<p>qRT-PCR analysis of Tfr1 mRNA (<b>A</b>), Tfr2 mRNA (<b>B</b>), Id1 mRNA (<b>C</b>), Smad6 mRNA (...
<p>Transferrin saturation (TS, <b>A</b>) and non-heme liver (LIC, <b>B</b>) iron content were measur...
A-C: Liver Hamp, Id1 and Bmp6 mRNA content, expressed as ΔCT relative to Actb mRNA content. Male C57...
A-C: Liver Hamp, Id1 and Smad7 mRNA content in samples prepared from control C57BL/6 mice (C), EPO-t...
<div><h3>Introduction</h3><p>Hemojuvelin (Hjv) is a key component of the signaling cascade that regu...
INTRODUCTION: Hemojuvelin (Hjv) is a key component of the signaling cascade that regulates liver hep...
<p>Five male wild type (WT) and five <i>Hjv-</i>/- mice at ∼10-weeks old were used for the studies. ...
<p>C57BL/6 wild type mice were fed with iron replete diet (IR), or iron-rich diet for 3 days (Fe die...
<p>Tissues were taken from <i>Hbb</i><sup><i>th3/+</i></sup>, <i>RBC14</i> and <i>hbd</i> mice, and ...
<p>(A) Liver and spleen non-heme iron concentrations. (B) SI and TS%. (C–E) Liver mRNA levels of <i>...
<p>(A) Time course of liver and spleen non-heme iron concentrations after switching to an iron-defic...
<p>Iron was administered to male C57BL/6 mice as iron polyisomaltosate at 200 mg/kg, erythropoietin ...
<p>(A) Liver and spleen non-heme iron concentrations. (B) Serum iron concentration (SI, µg/dL) and p...
<p>Immunoblots of Hjv protein in liver crude membrane fractions. Panel A: Detection with primary ant...
<p>Iron levels were determined as described in <i>Methods</i>. Results are depicted graphically, wit...
<p>qRT-PCR analysis of Tfr1 mRNA (<b>A</b>), Tfr2 mRNA (<b>B</b>), Id1 mRNA (<b>C</b>), Smad6 mRNA (...
<p>Transferrin saturation (TS, <b>A</b>) and non-heme liver (LIC, <b>B</b>) iron content were measur...
A-C: Liver Hamp, Id1 and Bmp6 mRNA content, expressed as ΔCT relative to Actb mRNA content. Male C57...