<p><b>A.</b> Relative methylation frequency (% methylation in tumor minus % methylation in adjacent normal) stratified by race; AA (n = 32) and EA (n = 33; Mann-Whitney). Adj. P: adjusted P value (Bonferroni) <b>B.</b> Relative methylation frequency stratified by ER- negative (−) patients with age<50 (17 cases in total; 8 AA cases and 9 EA cases) P value is shown (Mann-Whitney). <b>C.</b> Percentage methylation frequency in breast tumor cases stratified by age (age<50: n = 31; age≥50: n = 34). P value is shown (Mann-Whitney).</p
<p>Mean (+/-SD) methylation levels plotted against CpG site position along the chromosome in relatio...
<p>(A) Color-coded representation of DNA methylation in tumors from the combined PCa1 + PCa2 cohort....
<p>Panel A shows a heat map of DNA methylation resulting from an unsupervised cluster analysis of hi...
<p>Percentage methylation frequency stratified by subtype: <b>A.</b> Triple-negative (TN) tumors (n ...
<p>Number and percentage of low/intermediate- and high-grade tumours that are methylated for each of...
<p>†Calculated as any level of methylation detected within the 19 genes tested.</p><p>*significantly...
<p>The percentage of DNA methylation levels at promoter CpG islands were analyzed in bisulfite-modif...
<p>List of the top 10 genes that were hypermethylated in at least 85% of benign and malignant tumor ...
<p><b>A.</b> Genes commonly methylated in >95% of all samples.</p><p><b>B.</b> Genes methylated in a...
Purpose: To provide a molecular rationale for negative prognostic factors more prevalent in African-...
Purpose: To provide a molecular rationale for negative prognostic factors more prevalent in African-...
DNA methylation is an epigenetic modification that occurs when a methyl group is added to cytosine s...
<p>Calculation of the <i>PGP9.5</i> or <i>VGF</i> gene to <i>β-actin</i> ratios was based on the flu...
<p>The Kaplan-Meier curves for genes (DSP, EPHB6, HCK, IL18, IRAK3 and KIT) whose hypermethylation w...
<p>Number, and percentages (in parentheses), of positive samples for each gene using different scori...
<p>Mean (+/-SD) methylation levels plotted against CpG site position along the chromosome in relatio...
<p>(A) Color-coded representation of DNA methylation in tumors from the combined PCa1 + PCa2 cohort....
<p>Panel A shows a heat map of DNA methylation resulting from an unsupervised cluster analysis of hi...
<p>Percentage methylation frequency stratified by subtype: <b>A.</b> Triple-negative (TN) tumors (n ...
<p>Number and percentage of low/intermediate- and high-grade tumours that are methylated for each of...
<p>†Calculated as any level of methylation detected within the 19 genes tested.</p><p>*significantly...
<p>The percentage of DNA methylation levels at promoter CpG islands were analyzed in bisulfite-modif...
<p>List of the top 10 genes that were hypermethylated in at least 85% of benign and malignant tumor ...
<p><b>A.</b> Genes commonly methylated in >95% of all samples.</p><p><b>B.</b> Genes methylated in a...
Purpose: To provide a molecular rationale for negative prognostic factors more prevalent in African-...
Purpose: To provide a molecular rationale for negative prognostic factors more prevalent in African-...
DNA methylation is an epigenetic modification that occurs when a methyl group is added to cytosine s...
<p>Calculation of the <i>PGP9.5</i> or <i>VGF</i> gene to <i>β-actin</i> ratios was based on the flu...
<p>The Kaplan-Meier curves for genes (DSP, EPHB6, HCK, IL18, IRAK3 and KIT) whose hypermethylation w...
<p>Number, and percentages (in parentheses), of positive samples for each gene using different scori...
<p>Mean (+/-SD) methylation levels plotted against CpG site position along the chromosome in relatio...
<p>(A) Color-coded representation of DNA methylation in tumors from the combined PCa1 + PCa2 cohort....
<p>Panel A shows a heat map of DNA methylation resulting from an unsupervised cluster analysis of hi...