Time series of a simulated epidemic in a population in which there is no transmission between adults (black) and children (grey), in the absence (left) or presence (right) of an intervention.

<p>Broken line: susceptible; solid line: infected. CA_AW: Cumulative attack rate (adults, with whole population as the denominator); CA_CW: Cumulative attack rate (children, with whole population as the denominator). Infection was re-introduced into the population on day 300. The intervention (<i>f_AA</i> = <i>f_AC</i> = <i>f_CA</i> = <i>f_CC</i> = 1) started on day 100 (when the children’s epidemic is at its peak) and lasted until the first outbreak was over. β_AC = β_CA = 0; R_0A = 1.25; R_0C = 2. 50% adults; 50% children. All other parameters and initial conditions are listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0036573#pone-0036573-t001" target="_blank">Tables 1</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0036573#pone-0036573-t002" target="_blank">2</a>.