Growth of metastases in <i>PyMT</i>, <i>Lcn2</i>+/+ and <i>PyMT</i>, <i>Lcn2</i>−/− mice.

<p>Lipocalin-2-deficiency has no statistical significant effect on total volume (t-test, p = 0.09) or number (t-test, p = 0.09) of lung metastases derived from primary mammary tumors (n = 33 for <i>PyMT, Lcn2</i>+/+ and n = 26 for <i>PyMT, Lcn2</i>−/−). A, volumes of lung metastases in <i>PyMT</i>, <i>Lcn2</i>+/+ and <i>PyMT, Lcn2</i>−/− mice. Dots at 0 indicate mice without metastases. B, total numbers of lung metastases in <i>PyMT, Lcn2</i>+/+ and <i>PyMT</i>, <i>Lcn2</i>−/− mice. Horizontal bars indicate medians. Abbreviations: <i>PyMT: MMTV-PyMT</i>.