Multiplicative interaction between Chr. 22q12 (rs2412971) and Chr. 1q32 (rs6677604) loci.
- Krzysztof Kiryluk (156863)
- Yifu Li (156864)
- Simone Sanna-Cherchi (156865)
- Mersedeh Rohanizadegan (156866)
- Hitoshi Suzuki (16714)
- Frank Eitner (156867)
- Holly J. Snyder (156868)
- Murim Choi (147853)
- Ping Hou (17213)
- Francesco Scolari (13256)
- Claudia Izzi (156869)
- Maddalena Gigante (156870)
- Loreto Gesualdo (156871)
- Silvana Savoldi (156872)
- Antonio Amoroso (13258)
- Daniele Cusi (136954)
- Pasquale Zamboli (156875)
- Bruce A. Julian (156876)
- Jan Novak (156878)
- Robert J. Wyatt (156879)
- Krzysztof Mucha (156880)
- Markus Perola (62544)
- Kati Kristiansson (149853)
- Alexander Viktorin (156882)
- Patrik K. Magnusson (156885)
- Gudmar Thorleifsson (156887)
- Unnur Thorsteinsdottir (49155)
- Kari Stefansson (26484)
- Anne Boland (151261)
- Marie Metzger (156894)
- Lise Thibaudin (156897)
- Christoph Wanner (156898)
- Kitty J. Jager (143850)
- Shin Goto (156902)
- Dita Maixnerova (156905)
- Hussein H. Karnib (156906)
- Judit Nagy (156909)
- Ulf Panzer (156912)
- Jingyuan Xie (156916)
- Nan Chen (142925)
- Vladimir Tesar (156920)
- Ichiei Narita (156924)
- Francois Berthoux (156926)
- Jürgen Floege (13260)
- Benedicte Stengel (156928)
- Hong Zhang (25820)
- Richard P. Lifton (147862)
- Ali G. Gharavi (156930)
Publication date
June 2012
DOIAbstract
<p>The allelic effects of rs2412971-A by genotype class of rs9275596 (top signal in the HLA, no interaction) and rs6677604 (top signal in at <i>CFHR1/R3</i> locus on Chr. 1q32, significant interaction). The protective effect of rs2412971-A allele is reversed in homozygotes for the rs6677604-A allele, which tags a deletion in <i>CFHR3/R1</i>. The allelic effects are expressed on the log-odds scale and correspond to beta coefficients of the logistic regression model. Error bars correspond to 95% confidence intervals.</p
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