<p>Logistic regression modeling showed that the joint effects between rs1063192 and rs7916697 were interactive (<i>P</i>-interaction = 2.80E−5).The joint odds ratios were estimated for combinations of protective genotypes of rs1063192 (in the dominant model) or rs7916697 (in the dominant model) compared with the combination of both risk genotypes (homozygous major alleles for both markers).</p
Understanding the genetic background of complex diseases requires the expansion of studies beyond un...
<p>The logits of genotype combinations from models 1, 2, 3, 4, 7, 13, 14 and 19 are depicted in this...
<p>Only significant interactions between two loci, as identified by logistic regression, are present...
<p>The allelic effects of rs2412971-A by genotype class of rs9275596 (top signal in the HLA, no inte...
<p>Type 1 represents a DD interaction between SNPs a and b while Type 2 represents RR interaction be...
<p>The number of significant interactions observed is less than one might expect by chance.</p><p>P ...
<p>Each entry in the tables represents the risk of the corresponding genotype combination relative t...
a<p>SNPs were classified as wild-type genotype and heterozygote/homozygote genotypes. The wild-type ...
∧<p>One sample did not amplify when this marker was tested.</p>*<p>risk allele, odds ratios are calc...
+<p>AP = attributable proportion.</p>*<p>Wald test for interaction term in logistic regression model...
<p>The interaction shows between (A) rs1024611 and rs4586. Heterozygous 1/2 (AG); homozygous 1/1(AA)...
<p>H1: Exposed to one copy of risk alleles; H2: Exposed to two copies of risk allele; H3: Exposed to...
ABSTRACT The identification of gene–gene and gene–environment interaction in human traits and diseas...
<p>Bold-faced values indicate significant difference.</p>*<p>Two-sided χ<sup>2</sup> test for the di...
a<p>Case numbers reduced from GWAS according to the availability of both, parent genotypes and compl...
Understanding the genetic background of complex diseases requires the expansion of studies beyond un...
<p>The logits of genotype combinations from models 1, 2, 3, 4, 7, 13, 14 and 19 are depicted in this...
<p>Only significant interactions between two loci, as identified by logistic regression, are present...
<p>The allelic effects of rs2412971-A by genotype class of rs9275596 (top signal in the HLA, no inte...
<p>Type 1 represents a DD interaction between SNPs a and b while Type 2 represents RR interaction be...
<p>The number of significant interactions observed is less than one might expect by chance.</p><p>P ...
<p>Each entry in the tables represents the risk of the corresponding genotype combination relative t...
a<p>SNPs were classified as wild-type genotype and heterozygote/homozygote genotypes. The wild-type ...
∧<p>One sample did not amplify when this marker was tested.</p>*<p>risk allele, odds ratios are calc...
+<p>AP = attributable proportion.</p>*<p>Wald test for interaction term in logistic regression model...
<p>The interaction shows between (A) rs1024611 and rs4586. Heterozygous 1/2 (AG); homozygous 1/1(AA)...
<p>H1: Exposed to one copy of risk alleles; H2: Exposed to two copies of risk allele; H3: Exposed to...
ABSTRACT The identification of gene–gene and gene–environment interaction in human traits and diseas...
<p>Bold-faced values indicate significant difference.</p>*<p>Two-sided χ<sup>2</sup> test for the di...
a<p>Case numbers reduced from GWAS according to the availability of both, parent genotypes and compl...
Understanding the genetic background of complex diseases requires the expansion of studies beyond un...
<p>The logits of genotype combinations from models 1, 2, 3, 4, 7, 13, 14 and 19 are depicted in this...
<p>Only significant interactions between two loci, as identified by logistic regression, are present...