DEC1 induces cellular senescence and inhibits cell growth in vitro.
- Qing Xu (71204)
- Peiqing Ma (149155)
- Chenfei Hu (149157)
- Lechuang Chen (149159)
- Liyan Xue (149161)
- Zaozao Wang (149164)
- Mei Liu (41760)
- Hongxia Zhu (118797)
- Ningzhi Xu (129180)
- Ning Lu (22589)
Publication date
July 2012
DOIAbstract
<p>(A) SA-β-Gal staining assay was performed and senescent cell percentage was counted 48 h after transfection in EC9706 cells. (B) Protein expressions were analyzed by western blotting 48 h after transfection in EC9706 and HEK293 cells. (C) Growth curves of EC9706 and HEK293 cells after transfection with pCMV6-XL5-DEC1 and control plasmids. (D) Cells were seeded 24 h after transfection and colony number was counted two weeks G418 selection. Cotransfection efficiency was analyzed by western blotting. (*, P<0.05 as compared with ctrl.).</p
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